Antibiotic Usage and Resistance; Knowledge and Practices Before and After Educational Sessions

Antibiotics Clinical Trial

Official title:

Antibiotic Usage and Resistance - A Survey on Knowledge and Practices Among Second Year Dental Students and Patients Attending Misr International University Dental Clinics Before and After Educational Sessions

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04493008
• Other study ID #: PUB 2123001
• Status: Completed
• Phase: N/A
• Start date: February 1, 2018
• Est. completion date: June 30, 2020

Study information

• Verified date: July 2020
• Source: Misr International University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The inappropriate use of antibiotics by patients not only increases the growth of resistant bacterial strains but also, may lead to adverse side effects that range from gastrointestinal disturbances to fatal anaphylactic shock. To meet the challenges faced by the spread of antibiotics resistance, different approaches have been taken worldwide. One of the approaches which are commonly proposed is to engage instructional and educational campaigns among the health care personnel and the general population about antibiotic resistance and its dangerous consequences.The present study aims at assessing the knowledge, practices of antibiotic uses and resistance before and after educational sessions among second year dental students and a group of patients attending MIU Dental Clinics.

Description:

Statement of problem: Dental students' and patients' knowledge about antibiotic uses are essential for overcoming antibiotic resistance. Antibiotic resistance is considered an important global public health problem and is recognized as a major cause of the emerging problem of antimicrobial agent resistance. The inappropriate use of antibiotics by patients not only increases the growth of resistant bacterial strains but also, may lead to adverse side effects that range from gastrointestinal disturbances to fatal anaphylactic shock. To meet the challenges faced by the spread of antibiotics resistance, different approaches have been taken worldwide. One of the approaches which are commonly proposed is to engage instructional and educational campaigns among the health care personnel and the general population about antibiotic resistance and its dangerous consequences.

Aim of the study: The present study aims at assessing the knowledge, practices of antibiotic uses and resistance before and after educational sessions among second year dental students and a group of patients attending MIU Dental Clinics.

Materials and Methods: The study will be conducted on (315) second year dental students through a pre-and post-educational sessions questionnaire. Students will receive training sessions for four hours during their dental public health course given by senior staff members before conducting educational sessions targeting patients attending MIU Dental Clinics. Educational sessions will include verbal and visual tools.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 310
• Est. completion date: June 30, 2020
• Est. primary completion date: December 1, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• Second year dental students at MIU during the Academic Year 2017/2018. Any patient over 18 years old attending the MIU Dental clinics, and agreeing to sign an informed consent to participate in the study

Exclusion Criteria:

• Patients with mental disorders, deaf, and blind patients will be excluded from the study because the educational sessions will include verbal and visual tools.

Related Conditions & MeSH terms

• Antibiotics

Intervention

Behavioral:
• Experimental: Educational session
Each patient will receive educational session consisting of face-to-face interview, administration of posters, brochures and pamphlets.

Locations

Country	Name	City	State
Egypt	Faculty of Oral & Dental Medicine	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Misr International University

Country where clinical trial is conducted

Egypt, 

References & Publications (23)

Abu-Mostafa NA, Al-Mejlad NJ, Al-Yami AS, Al-Sakhin FZ, Al-Mudhi SA. A survey of awareness related to the use of antibiotics for dental issues among non-medical female university students in Riyadh, Saudi Arabia. J Infect Public Health. 2017 Nov - Dec;10(6):842-848. doi: 10.1016/j.jiph.2017.01.015. Epub 2017 Feb 21. — View Citation

Aljadhey H, Assiri GA, Mahmoud MA, Al-Aqeel S, Murray M. Self-medication in Central Saudi Arabia. Community pharmacy consumers' perspectives. Saudi Med J. 2015 Mar;36(3):328-34. doi: 10.15537/smj.2015.3.10523. — View Citation

André M, Vernby A, Berg J, Lundborg CS. A survey of public knowledge and awareness related to antibiotic use and resistance in Sweden. J Antimicrob Chemother. 2010 Jun;65(6):1292-6. doi: 10.1093/jac/dkq104. Epub 2010 Apr 1. — View Citation

Annual report of the chief medical officer, volume two, 2011. Infections and the rise of antimicrobial resistance.

Armitage, P., Berry, G., & Matthews, J. N. S. Statistical methods in medical research. Wiley Online Library,4rth edition, 2008

Azevedo MM, Pinheiro C, Yaphe J, Baltazar F. Portuguese students' knowledge of antibiotics: a cross-sectional study of secondary school and university students in Braga. BMC Public Health. 2009 Sep 23;9:359. doi: 10.1186/1471-2458-9-359. — View Citation

Butler CC, Rollnick S, Pill R, Maggs-Rapport F, Stott N. Understanding the culture of prescribing: qualitative study of general practitioners' and patients' perceptions of antibiotics for sore throats. BMJ. 1998 Sep 5;317(7159):637-42. — View Citation

Chen C, Chen YM, Hwang KL, Lin SJ, Yang CC, Tsay RW, Liu CE, Young TG. Behavior, attitudes and knowledge about antibiotic usage among residents of Changhua, Taiwan. J Microbiol Immunol Infect. 2005 Feb;38(1):53-9. — View Citation

Cope AL, Wood F, Francis NA, Chestnutt IG. General dental practitioners' perceptions of antimicrobial use and resistance: a qualitative interview study. Br Dent J. 2014 Sep;217(5):E9. doi: 10.1038/sj.bdj.2014.761. — View Citation

Dailey YM, Martin MV. Are antibiotics being used appropriately for emergency dental treatment? Br Dent J. 2001 Oct 13;191(7):391-3. — View Citation

Khan A K A, Banu G, K K R. Antibiotic Resistance and Usage-A Survey on the Knowledge, Attitude, Perceptions and Practices among the Medical Students of a Southern Indian Teaching Hospital. J Clin Diagn Res. 2013 Aug;7(8):1613-6. doi: 10.7860/JCDR/2013/6290.3230. Epub 2013 Jul 1. — View Citation

Lewis MA. Why we must reduce dental prescription of antibiotics: European Union Antibiotic Awareness Day. Br Dent J. 2008 Nov 22;205(10):537-8. doi: 10.1038/sj.bdj.2008.984. — View Citation

Mahajan, Dr. Manali. (2014). A Questionnaire based Survey on the Knowledge, Attitude and Practises about Antimicrobial Resistance and Usage among the Second year MBBS Students of a Teaching tertiary care Hospital in Central India. International Journal of Pharmacological Research.

McManus P, Hammond ML, Whicker SD, Primrose JG, Mant A, Fairall SR. Antibiotic use in the Australian community, 1990-1995. Med J Aust. 1997 Aug 4;167(3):124-7. — View Citation

Metlay JP, Stafford RS, Singer DE. National trends in the use of antibiotics by primary care physicians for adult patients with cough. Arch Intern Med. 1998 Sep 14;158(16):1813-8. — View Citation

Simpson SA, Wood F, Butler CC. General practitioners' perceptions of antimicrobial resistance: a qualitative study. J Antimicrob Chemother. 2007 Feb;59(2):292-6. Epub 2006 Nov 16. — View Citation

Srinivasan A, Song X, Richards A, Sinkowitz-Cochran R, Cardo D, Rand C. A survey of knowledge, attitudes, and beliefs of house staff physicians from various specialties concerning antimicrobial use and resistance. Arch Intern Med. 2004 Jul 12;164(13):1451-6. — View Citation

Sweeney LC, Dave J, Chambers PA, Heritage J. Antibiotic resistance in general dental practice--a cause for concern? J Antimicrob Chemother. 2004 Apr;53(4):567-76. Epub 2004 Feb 25. Review. — View Citation

Tulip DE, Palmer NO. A retrospective investigation of the clinical management of patients attending an out of hours dental clinic in Merseyside under the new NHS dental contract. Br Dent J. 2008 Dec 20;205(12):659-64; discussion 648. doi: 10.1038/sj.bdj.2008.1044. Epub 2008 Dec 5. — View Citation

Vanden Eng J, Marcus R, Hadler JL, Imhoff B, Vugia DJ, Cieslak PR, Zell E, Deneen V, McCombs KG, Zansky SM, Hawkins MA, Besser RE. Consumer attitudes and use of antibiotics. Emerg Infect Dis. 2003 Sep;9(9):1128-35. — View Citation

WHO Library Cataloguing-in-Publication Data. Antibiotic resistance: Multi-country public awareness survey .World Health Organization. 2015.

Wise R, Hart T, Cars O, Streulens M, Helmuth R, Huovinen P, Sprenger M. Antimicrobial resistance. Is a major threat to public health. BMJ. 1998 Sep 5;317(7159):609-10. — View Citation

Wright EP, Jain P. Survey of antibiotic knowledge amongst final year medical students. J Antimicrob Chemother. 2004 Mar;53(3):550-1. Epub 2004 Feb 4. — View Citation

* Note: There are 23 references in all — Click here to view all references

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Knowledge about antibiotics	Percentage of correct answers	4 months
Secondary	Awareness level	Percentage	4 months