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Prosthesis Infection and One-step Exchange: Pretreatment by Targeted Antibiotic Therapy in At-risk Patients

Antibiotic Resistant Infection Clinical Trial

Official title:
Prosthesis Infection and One-step Exchange: Pretreatment by Targeted Antibiotic Therapy in

Clinical Trial Summary

One-step exchange arthroplasty is more and more used in the treatment of chronic infections, especially in patients at risk anesthetic. This strategy is not recommended in patients infected with multidrug-resistant organisms or difficult to treat because of a risk of bacterial persistence on the new implant. Antibiotic pretreatment by a narrow-spectrum molecule and for which resistance acquisition is difficult might be of interest to try to reduce the inoculum and avoid contamination of the new implant.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03848091
Study type Observational
Source Hospices Civils de Lyon
Contact
Status Completed
Phase
Start date April 1, 2016
Completion date January 1, 2018
View Details
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