Anthocyanins Clinical Trial
Official title:
A Randomized Placebo-controlled Cross-over Design Study Investigating the Effects of a Plant Polyphenol Blend on the Intestinal Inflammatory and Metabolic Responses to a High Fat Meal in Healthy Subjects
This study will investigate the beneficial effects of supplementation with a plant polyphenol
blend rich in anthocyanins on parameters of inflammation and metabolic responses following a
challenge with a high-fat (HF) meal.
The investigators will use a randomized crossover study to investigate the effects of: 1)
placebo (control); 2) plant polyphenol blend rich in anthocyanins; on systemic inflammatory
markers (endotoxemia, cytokines, NF-κB), glucose and lipid metabolic responses following
consumption of a high-fat (HF) meal in healthy subjects. The high-fat meal (320 g) consists
of English muffin bread, sausage, egg and cheese, obtained from US market and completed with
palm fat. The total energy content of the high-fat meal is 1,026 Kcal with 70.5 g of fat
(29.8 g of saturated fat), 270 mg of cholesterol, 65 g carbohydrate, 5.2 g sugar, and 33 g
protein with a total of 62% energy originated from fat, 25% from carbohydrates and 13% from
protein. The high-fat meal will be standard and it will not be adjusted for large and small
participants.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT04637945 -
Inflammatory and Metabolic Responses to Long-term Dietary Supplementation With Anthocyanin-rich Blend
|
N/A |