Clinical Trials Logo
  1. Home
  2. Anovulation
  3. NCT01289756

Influence of Pharmacogenetic Factors, Paroxetine and Clarithromycin on Pharmacokinetics of Clomiphene

Anovulation Clinical Trial

Official title:
Influence of Pharmacogenetic Factors, Paroxetine and Clarithromycin on Pharmacokinetics of Clomiphene

Clinical Trial Summary

Aim of the study is the clinical validation of the metabolism and the pharmakokinetic of Clomifen in correlation to CYP2D6 and inhibition of CYP3A4.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Pharmacokinetics Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

  • Anovulation
  • Cytochrome P450 CYP3A Enzyme Deficiency
  • Disorder Due Cytochrome P450 CYP2D6 Variant
Clinical Trial Details
NCT number NCT01289756
Study type Interventional
Source Robert Bosch Gesellschaft für Medizinische Forschung mbH
Contact
Status Completed
Phase Phase 1
Start date December 2009
Completion date November 2014
View Details
See also
  Status Clinical Trial Phase
Completed NCT01653743 - Trial to Assess the Clinical Efficacy and Safety of MSJ-0011 in Inducing Ovulation in Anovulatory or Oligo-ovulatory Japanese Women Phase 3
Completed NCT00327366 - Effect of Bright Light on Sex Hormones and Ovulation in Humans N/A
Not yet recruiting NCT02551367 - Letrozole Versus Clomiphene Citrate for Ovulation Induction in Women With Poly Cystic Ovary Syndrome ( PCOS ) Phase 2
Completed NCT01923194 - Evaluation of Efficacy and Safety of Highly Purified Urofollitropin for Ovulation Induction in Chinese Females Phase 3
Completed NCT01008319 - Traditional Clomiphene Citrate Administration vs. Stair-step Approach Phase 3
Completed NCT00239603 - Efficacy Study of the OV-Watch™ Personal Fertility Monitor for Women Using Clomiphene Citrate. Phase 4
Recruiting NCT02309047 - The Cycle Disturbances, OLigomenorrhea and Amenorrhea (COLA) Study & Biobank
Completed NCT03252223 - Ovarian Response to Recombinant Follicle Stimulating Hormone in Women With PCOS Phase 4
Completed NCT00492882 - Study of Mechanisms of Anovulation in Polycystic Ovary Syndrome Phase 4
Completed NCT02335879 - Phase III Clinical Study of Domestic Recombinant Human Follitropin for Injection to Treat WHO Class II Anovulation Phase 3
Completed NCT00471523 - Treatment of Anovulatory Infertility in PCOS Patients Phase 4
Completed NCT02703649 - Administration of Single High Dose Letrozole for Ovulation Induction Phase 4
Completed NCT00213148 - Comparison of Anastrozole Verses Clomiphene Citrate in Stimulating Follicular Growth and Ovulation in Infertile Women With Ovulatory Dysfunction Phase 2
Completed NCT03018314 - Serum Kisspeptin Levels in Infertile Women N/A
Completed NCT02710981 - Sildenafil Vaginal Gel Co-treatment With Clomiphene Citrate in Infertile Women With Thin Endometrium N/A
Recruiting NCT02186782 - Concomitant CC and E2 Versus CC Alone in Ovulation Induction Phase 4
Not yet recruiting NCT00665171 - Whole Genome Analysis for the Detection of Key Genes in the Polycystic Ovary Syndrome N/A
Withdrawn NCT03155828 - Using CPAP to Improve Menstruation in Women With Polycystic Ovarian Syndrome and Obstructive Sleep Apnea
Withdrawn NCT00453219 - FHA: Characterization of Metabolic Status, Brain Circuitry, and Stress-Reactivity N/A
Completed NCT00920634 - Protocol for Drug Use Investigation of Follistim Injection (Study P06132)(COMPLETED)