Effects of Resistance Strength Training on Functional Capacity and Well Being of Anorexic Patients

Anorexia Clinical Trial

Official title:

Effects of Resistance Strength Training on Functional Capacity and Well Being of Anorexic Patients; A Randomized Controlled Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00829946
• Other study ID #: R-0034/08
• Status: Completed
• Phase: N/A
• First received: January 26, 2009
• Last updated: January 26, 2009
• Start date: January 2008
• Est. completion date: March 2008

Study information

• Verified date: January 2009
• Source: Universidad Europea de Madrid
• Contact: n/a
• Is FDA regulated: No
• Health authority: Spain: Ethics Committee
• Study type: Interventional

Clinical Trial Summary

The purpose of the present randomized controlled trial was to determine the effects of a 3-month resistance training program (2 sessions/week) on the functional mobility and muscle function, muscular dynamic strength, body composition and quality of life of young anorexic outpatients (≤16 years). The investigators also assessed cardiorespiratory variables of clinical significance such as peak oxygen uptake.

Description:

A total of 22 outpatients [20 female (Tanner stage II-IV), 2 male (Tanner stage IV); age range: 12-16 years] were finally eligible and thus participated in the study.

Participants in the intervention group were enrolled in two training sessions per week for 12 weeks. Each session lasted 60-70 min and started at ~11:30 a.m., after the intra-hospital psychotherapy session. The program was individually supervised, i.e. one instructor for every three patients.

Each session started and ended with a low intensity 10-15min warm-up and cool-down period respectively, consisting of stretching exercises involving all major muscle groups. The core portion of the training session consisted of 11 strength exercises engaging the major muscle groups, i.e. bench press, shoulder press, leg extension, leg press, leg curl, abdominal crunch, low back extension, arm curl, elbow extension, seated row and lateral pull-down. For each exercise, the participants performed one set of 8-15 repetitions (total of ~ 20s duration) with resting periods of 1-2 min between exercises. The load was gradually increased as the strength of each child improved, i.e. from 20-30% of 6 repetition maximum (6RM) at the start of the program to 50-60% of 6RM at the end. Stretching exercises of the muscles involved in the previous exercises were performed during the rest periods (21).

Participants also performed isometric contractions of large muscle groups (6 sets of 3 repetitions each, 20-30s duration per repetition) with their own body weight (for lower body exercises) or barbells (1-3kg) for upper body.

Outcome measures:

• Anthopometry

• Cardiorespiratory fitness

• Muscular strength

• Functional mobility

• Quality of life

Recruitment information / eligibility

• Status: Completed
• Enrollment: 35
• Est. completion date: March 2008
• Est. primary completion date: January 2008
• Accepts healthy volunteers: No
• Gender: Female
• Age group: N/A to 16 Years

Eligibility

Inclusion Criteria:

• Diagnosis of restrictive anorexia nervosa

• Age = 16 years

• Undergoing intra-hospital psychotherapy and dietary counseling (two visits per week) in this Hospital

• Body mass index > 14.0 kg/m2

Exclusion Criteria:

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Anorexia

Intervention

Behavioral:
• Physical activity
Participants in the intervention group were enrolled in two training sessions per week for 12 weeks. The core portion of the training session consisted of 11 strength exercises engaging the major muscle groups, i.e. bench press, shoulder press, leg extension, leg press, leg curl, abdominal crunch, low back extension, arm curl, elbow extension, seated row and lateral pull-down. For each exercise, the participants performed one set of 8-15 repetitions (total of ~ 20s duration) with resting periods of 1-2 min between exercises. The load was gradually increased as the strength of each child improved, i.e. from 20-30% of 6 repetition maximum (6RM) at the start of the program to 50-60% of 6RM at the end. Participants also performed isometric contractions of large muscle groups (6 sets of 3 repetitions each, 20-30s duration per repetition) with their own body weight (for lower body exercises) or barbells (1-3kg) for upper body.

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Universidad Europea de Madrid	Hospital Infantil Universitario Niño Jesús, Madrid, Spain

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Quality of life			Yes
Primary	Anthropometry			Yes
Primary	Functional mobility			Yes
Secondary	Muscular strength			Yes
Secondary	Cardiorespiratory fitness			Yes