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Anorexia clinical trials

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NCT ID: NCT00183586 Completed - Eating Disorders Clinical Trials

Comparing the Effectiveness of Three Types of Therapy for the Treatment of Anorexia Nervosa in Adolescents

Start date: April 2004
Phase: Phase 2
Study type: Interventional

This study will compare specific family therapy, standard family systems therapy, and standard individual psychotherapy to determine which is most effective in treating adolescent anorexia nervosa.

NCT ID: NCT00176150 Recruiting - Anorexia Nervosa Clinical Trials

Drug Transport in Patients With Anorexia Nervosa

Start date: n/a
Phase: N/A
Study type: Observational

The aim of this study is to investigate whether patients with anorexia nervosa have elevated plasma cholesterol levels and, if elevated plasma cholesterol levels influence drug transport by the ABC-transporter P-gp (P-glycoprotein, MDR 1/ABCB1). We will isolate peripheral blood mononuclear cells (PBMCs) and total RNA from the blood of patients with anorexia nervosa and healthy subjects as control. PBMCs will be used for quantitative cholesterol determination and for measuring the activity of P-gp using a FACS (fluorescence-activated cell sorting) method (rhodamine123 efflux). Total RNA will be used for quantitative expression analysis of P-gp by reverse transcriptase real time PCR.

NCT ID: NCT00149786 Completed - Eating Disorders Clinical Trials

Effectiveness of Family-Based Versus Individual Psychotherapy in Treating Adolescents With Anorexia Nervosa

Start date: October 2004
Phase: Phase 1
Study type: Interventional

This study will compare the effectiveness of family-based therapy versus individual psychotherapy for the treatment of adolescent anorexia nervosa.

NCT ID: NCT00140426 Completed - Anorexia Nervosa Clinical Trials

A Double-blind, Placebo Controlled Trial of Risperidone for the Treatment of Anorexia Nervosa

Start date: August 2004
Phase: Phase 4
Study type: Interventional

The aim of this pilot study is to determine the safety and efficacy of risperidone for the treatment of anorexia nervosa. Hypothesis 1: Subjects on risperidone will show a more significant decrease in body image distortion and Eating Disorder Inventory -2 scores than subjects on placebo. Hypothesis 2: Subjects on risperidone will reach and maintain at or above 90% Ideal body weight sooner than controls.

NCT ID: NCT00089843 Completed - Anorexia Nervosa Clinical Trials

Bone Loss in Women With Anorexia Nervosa

Start date: June 2003
Phase: Phase 2/Phase 3
Study type: Interventional

Women with Anorexia Nervosa have been found to have low bone density. The study will determine whether administration of low doses of a natural hormone, testosterone and/or risedronate, a medication to help prevent bone breakdown will improve or prevent bone loss in this condition.

NCT ID: NCT00088153 Completed - Anorexia Nervosa Clinical Trials

Effects of Anorexia Nervosa on Bone Mass in Adolescents

Start date: July 2003
Phase: Phase 2/Phase 3
Study type: Interventional

This study is to determine the effects of anorexia nervosa on bone mass and hormone levels in adolescents. Whether administration of estrogen, a normal hormone present during puberty, can help maintain bone development in girls with anorexia nervosa will be determined.

NCT ID: NCT00081250 Completed - Clinical trials for Unspecified Adult Solid Tumor, Protocol Specific

Creatine in Treating Patients With Cancer-Associated Weight Loss

Start date: December 2004
Phase: Phase 3
Study type: Interventional

RATIONALE: It is not yet known whether the supplement creatine is effective in increasing weight and improving appetite and quality of life in patients who have cancer. PURPOSE: This randomized phase III trial is studying how well creatine works in increasing weight and improving appetite and quality of life in patients with weight loss caused by cancer.

NCT ID: NCT00046904 Completed - Clinical trials for Unspecified Adult Solid Tumor, Protocol Specific

Etanercept in Treating Cancer-Related Cachexia and Anorexia in Patients With Advanced Cancer

Start date: May 2003
Phase: Phase 3
Study type: Interventional

RATIONALE: Etanercept is a substance that is being studied as a treatment for cachexia (weight loss) and anorexia (lack of appetite) in patients who have cancer. It is not yet known whether etanercept is effective in improving cancer-related cachexia and anorexia. PURPOSE: Randomized phase III trial to determine the effectiveness of etanercept in treating cancer-related cachexia and anorexia in patients who have advanced cancer.

NCT ID: NCT00040885 Completed - Lung Cancer Clinical Trials

Docetaxel With or Without Infliximab in Treating Weight Loss, Loss of Appetite, and Fatigue in Patients With Unresectable Non-Small Cell Lung Cancer (Infliximab Treatment Discontinued Effective 10/05/05)

Start date: October 2002
Phase: Phase 3
Study type: Interventional

RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop tumor cells from dividing so they stop growing or die. Infliximab may improve cancer-related weight loss, lack of appetite, and fatigue. It is not yet known whether docetaxel is more effective with or without infliximab in preventing weight loss and fatigue in patients with advanced cancer. (Infliximab treatment discontinued effective 10/05/05) PURPOSE: Randomized phase III trial to determine the effectiveness of docetaxel with or without infliximab in preventing weight loss, loss of appetite, and fatigue in patients who have unresectable non-small cell lung cancer. (Infliximab treatment discontinued effective 10/05/05)

NCT ID: NCT00031785 Completed - Lung Cancer Clinical Trials

Megestrol in Treating Patients Who Are Undergoing Radiation Therapy for Lung Cancer

Start date: September 1, 2000
Phase: Phase 3
Study type: Interventional

RATIONALE: Megestrol helps improve appetite. It is not yet known if megestrol is effective in limiting weight loss in patients who are undergoing radiation therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of megestrol in limiting weight loss in patients who are undergoing radiation therapy for lung cancer.