Studies of Neuroendocrine and Energy Metabolism in Patients With Eating Disorders

Anorexia Nervosa Clinical Trial

Official title:

Studies of Neuroendocrine and Energy Metabolism in Patients With Eating Disorders

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00631605
• Other study ID #: 200705061R
• Status: Completed
• Phase: N/A
• First received: March 3, 2008
• Last updated: March 1, 2009
• Start date: May 2007
• Est. completion date: January 2009

Study information

• Verified date: March 2009
• Source: National Taiwan University Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Taiwan: Department of Health
• Study type: Observational

Clinical Trial Summary

This study aims to investigate neuroendocrine, autonomic functioning, and energy metabolism in patients with eating disorder and their relationships with psychopathology of eating disorders (eating patterns, depression, and personality) in these patients.

Description:

The study subjects include female patients with DSM-IV diagnosis of AN (n = 30), BN (n = 60) and age-controled normal subjects (n = 30). They will receive a clinical interview and are asked to complete several self-administered questionnaires which included eating-related questionnaires, general psychological functioning scales and personality scales. After overnight fast, each subject undergoes a blood sample collection for neuroendocrine examination, body composition examination using BIA method, basal metabolic rate measurement by indirect calorimetry, and ECG in the morning between 0800 and 0900. Clinical patients would be asked to repeat filling the self-rating scales, weight and body fat measurement, as well as blood drawing again 2 months after treatment.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 112
• Est. completion date: January 2009
• Est. primary completion date: January 2009
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Subjects who fulfilled DSM-IV diagnosis of anorexia nervosa or bulimia nervosa

• Normal controls

Exclusion Criteria:

• Any major psychiatric disorders

• Use of psychoactive medications

• Drug and alcohol abuse

• Medical problems (cardiovascular condition and endocrine disorders)

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Anorexia Nervosa
• Bulimia
• Bulimia Nervosa
• Eating Disorders

Locations

Country	Name	City	State
Taiwan	National Taiwan University Hospital	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan,