Ankylosing Spondylitis Clinical Trial
Official title:
The Clinical Research of the Traditional Chinese Medicine Bawei Shenqi Pill in the Treatment of the Kidney Yang Deficiency Type of Ankylosing Spondylitis
The purpose of this study is to determine whether Bawei Shenqi Pill is effective in the treatment of active ankylosing spondylitis (AS).
Ankylosing spondylitis is a chronic inflammatory disease, which mainly invades sacroiliac
joint, spinal osteoid process, paraspinal soft tissue and peripheral joints, and can be
accompanied by extraarticular manifestations, in severe cases, spinal deformity and ankylosis
can occur. The overall prevalence rate of ankylosing spondylitis in China is about 0.3%, the
peak of which is 20 to 30 years old. although the prevalence rate is not high, the disability
rate is high, and the patients with ankylosing spondylitis are mainly young people of
childbearing age, which are in a critical period of work and study. If the disease can not be
controlled smoothly, it will seriously affect its learning and work efficiency, image
appearance and even the ability of daily life.
Bawei Shenqi Pill originates from Zhang Zhongjing's synopsis of the Golden Chamber, is the
representative prescription of warming and tonifying kidney yang, and is also suitable for
the pathogenesis of ankylosing spondylitis "deficiency of kidney yang". The purpose of this
study was to observe the therapeutic effect of Bawei Shenqi Pill on ankylosing spondylitis of
kidney-yang deficiency type through a randomized controlled clinical study. To clarify the
effect of Bawei Shenqi Pill on disease activity, joint function, TCM syndrome integral and
quality of life in patients with ankylosing spondylitis, and to provide basis for the
treatment of ankylosing spondylitis with Bawei Shenqi Pill.
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