Non-Steroidal Anti-inflammatory Drugs in Axial Spondyloarthritis

Status Terminated

Clinical Trial Summary

This is a 6-week randomized, double-blind trial of 4 different non-steroidal anti-inflammatory drugs in patients with axial spondyloarthritis to compare the change of pain score from baseline at 4 weeks to the change of pain score from baseline at 6 weeks.

Clinical Trial Description

Patients with ankylosing spondylitis or axial spondyloarthritis who fulfills the inclusion and exclusion criteria will be randomized into one of the four arms after an initial one week washout period, including: 1) indomethacin 75mg every 12 hours (Q12H); 2) diclofenac 75mg Q12H; 3) meloxicam 7.5mg Q12H; 4) celecoxib 200mg Q12H. The treatment length will be 6 weeks. Primary outcome is the change of pain score from baseline to week 4 and to week 6. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03473665
Study type	Interventional
Source	Columbia University
Contact
Status	Terminated
Phase	Phase 4
Start date	March 1, 2018
Completion date	August 2, 2019

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