Angina, Unstable Clinical Trial
Official title:
A Phase III Double-Blind, Placebo-Controlled Multicenter Study of Abciximab In Patients Undergoing High Risk Coronary Angioplasty (EPIC)
The purpose of this study is to evaluate the effectiveness and safety of abciximab (an anti-platelet therapy) versus placebo in patients undergoing high risk coronary angioplasty.
This is a randomized, double-blind, placebo-controlled, multicenter study evaluating the
efficacy and safety of abciximab, an anti-platelet therapy, in patients undergoing high risk
coronary angioplasty. The primary outcomes of the study include any of the following: the
number of deaths from any cause, or myocardial infarctions and recurrent ischemic events
requiring urgent intervention (e.g., repeat angioplasty, coronary artery bypass surgery,
intracoronary stent placement, or intra-aortic balloon pump).
Patients receive an abciximab bolus, abciximab bolus plus infusion, or placebo.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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