Enhanced Recovery After Surgery Protocol on Early Mobilization After Colorectal Surgery

Anesthesia Clinical Trial

Official title:

Compliance With Enhanced Recovery After Surgery Protocol on Early Mobilization After Colorectal Surgery in Tertiary Hospital in Indonesia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06065696
• Other study ID #: IndonesiaUAnes112
• Status: Completed
• Start date: February 1, 2023
• Est. completion date: April 30, 2023

Study information

• Verified date: September 2023
• Source: Indonesia University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Early mobilization is an important factor in increasing postoperative colorectal surgeries outcome. There are four components held by anesthesiologist in Enhanced Recovery After Surgery protocol for colorectal surgery in our hospital: post operative nausea and vomiting (PONV) prophylaxis, intraoperative fluid management, intraoperative multimodal analgesia, and postoperative opioid-free pain management. Although early mobilization affected by postoperative pain, vomiting and nausea, and fluid balance management, nonetheless, there is no clear evidence of how much each of these components will affect early mobilization.

Description:

Early mobilization is an important factor in increasing postoperative colorectal surgeries outcome. There are four components held by anesthesiologist in ERAS protocol for colorectal surgery in our hospital: PONV prophylaxis, intraoperative fluid management, intraoperative multimodal analgesia, and postoperative opioid-free pain management. Although early mobilization affected by postoperative pain, vomiting and nausea, and fluid balance management, nonetheless, there is no clear evidence of how much each of these components will affect early mobilization. This study was a retrospective cohort study by collecting secondary data from patients underwent elective colorectal surgery in our hospital from January 2020 to December 2022. The outcomes assessed were early mobilization rate and factors affecting it (PONV prophylaxis, intraoperative fluid management, intraoperative multimodal analgesia, and postoperative opioid-free pain management).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 343
• Est. completion date: April 30, 2023
• Est. primary completion date: April 30, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 60 Years

Eligibility

Inclusion criteria

• Patient underwent colorectal surgery in Cipto Mangunkusumo Hospital from 2020 to 2022

• Age 18-60 years old

• American Society of Anesthesiologist (ASA) physical status 1, 2, and 3

Exclusion criteria

• Patients who were not intubated on postoperative period

• Patients who had physical limitation during preoperative mobility test

Related Conditions & MeSH terms

• Anesthesia
• Colorectal
• Early Mobilization
• Enhanced Recovery After Surgery

Intervention

Procedure:
• Early mobilization
Patients who received early mobilization in postoperative period
• No early mobilization
Patients who did not receive early mobilization in postoperative period

Locations

Country	Name	City	State
Indonesia	Cipto Mangunkusumo Central National Hospital	Jakarta Pusat	DKI Jakarta

Sponsors (1)

Lead Sponsor	Collaborator
Indonesia University

Country where clinical trial is conducted

Indonesia, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Early mobilization	Number of patients who can walk within 24 hours after surgery	Within 24 hours after surgery
Primary	PONV prophylaxis	Number of patients who received prophylaxis given for PONV	Given during intraoperative period
Primary	Multimodal analgesia	Number of patients who got multimodal analgesia, which consists of epidural anesthesia or peripheral nerve block	Given during intraoperative period
Primary	Intraoperative fluid management	Number of patients who achieved fluid balance of zero or near zero	Given during intraoperative period
Primary	Postoperative pain management	Number of patients who received postoperative pain management without opioid	Immediately after surgery until discharge, assessed until hospital discharge, up to 50 days