The Quality of Recovery After General Anesthesia With Desflurane and Sevoflurane in Endoscopic Ureteral Lithotripsy

Anesthesia Clinical Trial

Official title:

The Quality of Recovery After General Anesthesia With Desflurane and Sevoflurane in Endoscopic Ureteral Lithotripsy

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04712162
• Other study ID #: 81/CN-HÐÐÐ
• Status: Completed
• Phase: N/A
• Start date: November 19, 2019
• Est. completion date: May 7, 2020

Study information

• Verified date: January 2021
• Source: Gia Dinh People Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The good quality of recovery after general anesthesia is one of goals for short procedures and ambulatory surgeries. The study's objective was to compare the quality of recovery after general anesthesia with desflurane and sevoflurane with laryngeal mask airway for endoscopic ureteral lithotripsy.

Description:

This is a randomized controlled trial. There were 60 cases of endoscopic ureteral lithotripsy under general anesthesia with laryngeal mask airway were enrolled. All cases were randomly divided into two group (desflurane or sevoflurane). Each group had 30 cases. Primary outcome was time to awakening. Secondary outcomes were time to wash-out of volatile anesthetics, time to extubation, irritation after awakening, and modified Aldrete score. Statistical analysis was performed by using Kaplan-Meieir curve and log-rank test for time to adequate depth of anesthesia and time to awakening; t-test for time to wash-out of volatile anesthetics; chi-square test for depth of anesthesia by PRST score, irritation after awakening and Aldrete score; Fisher test for adverse effects of volatile anesthetics. The research was approved by Gia Dinh People Hospital ethics committee

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: May 7, 2020
• Est. primary completion date: May 7, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• All eligible subjects who underwent endoscopic ureteral lithotripsy under general anesthesia
• ASA I and II

Exclusion Criteria:

• Contraindication to laryngeal mask airway.
• Indication for conversion to tracheal intubation during surgery.
• History of malignant hyperthermia.
• Pregnancy.
• Obese (BMI >25 kg/m2).
• Substances abuse.

Related Conditions & MeSH terms

• Anesthesia

Intervention

Other:
• Other
Compare time to awakening and quality of recovery after general anesthesia between two groups.

Locations

Country	Name	City	State
Vietnam	Anesthesiology Department of Gia Dinh People Hospital	Ho Chi Minh City

Sponsors (1)

Lead Sponsor	Collaborator
Gia Dinh People Hospital

Country where clinical trial is conducted

Vietnam, 

References & Publications (21)

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* Note: There are 21 references in all — Click here to view all references

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Time to awakening	Time required for awakening	After stopping volatile anesthetics to patient awakening, up to 30 minutes.
Secondary	Time to wash-out of volatile anesthetics	Time required for washing out volatile anesthetics	After stopping volatile anesthetics to complete wash-out of volatile anesthetics, up to 30 minutes
Secondary	Time to extubation	Time required for successful extubation.	After stopping volatile anesthetics to readiness for extubation, up to 30 minutes
Secondary	Irritation after awakening	Aono score >2	After awakening to eligible discharge, up to 2 hours.
Secondary	Adverse effects of volatile anesthetics	Hypotension, cough, nausea and vomitting.	After providing volatile anesthetics until they were stopped, up to 90 minutes