Mini-fluid Challenge as a Predictor of Fluid Response for Pneumoperitoneum Patient

Anesthesia Clinical Trial

Official title:

Mini-fluid Challenge as a Predictor of Fluid Response for Pneumoperitoneum Patient

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT03843411
• Other study ID #: 181239
• Status: Withdrawn
• Start date: October 2019
• Est. completion date: October 2020

Study information

• Verified date: January 2020
• Source: Changhua Christian Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to evaluate whether the change of stroke volume index(△SVI) induced by the rapid mini-fluid administration can predict fluid responsiveness in patients with pneumoperitoneum

Description:

Perioperative fluid management is significant important during surgery. The current trend tends to use goal-directed fluid therapy in surgery. Goal-directed fluid therapy refers to continuous monitoring of hemodynamic parameters during surgery and managing more accurate fluid administration based on the data obtained while promoting optimal tissue perfusion. Define fluid responsiveness with the hemodynamic parameters as to whether the cardiac output can be significantly increased after administration of fluid. Therefore, the advantage of predicting fluid responsiveness is that it can optimize the cardiac output and tissue perfusion while avoiding administering unnecessary fluid to patients.

The purpose of this study is to evaluate whether the change of stroke volume index(△SVI) induced by the rapid mini-fluid administration can predict fluid responsiveness in patients with pneumoperitoneum.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: October 2020
• Est. primary completion date: October 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 70 Years

Eligibility

Inclusion Criteria:

• receive operation that required pneumoperitoneum and FloTrac monitoring

• ASA 1~3

• age between 20 to 70 year old

Exclusion Criteria:

• patient who cannot understand the process and aim of the study

• patient with arrhythmia

• poor heart function(LVEF<50%, severe valvular disease, CAD)

• CKD

• pregnant patient

• patients allergic to voluven

Related Conditions & MeSH terms

• Anesthesia
• Pneumoperitoneum

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Changhua Christian Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	change of stroke volume index	record stroke volume index before and after mini-fluid challenge	1 hours