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NCT03624166 Clinical Trial

Impact of Sub-anesthetic Dose of Ketamine on Post Spinal Hypotension in Caesarean Delivery

Anesthesia Clinical Trial

Official title:
Impact of Sub-anesthetic Dose of Ketamine on Post Spinal Hypotension in Caesarean Delivery :Prospective , Randomized Double- Blinded Study

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03624166
Other study ID # FAMUS R 38/ 2018
Secondary ID
Status Completed
Phase Phase 4
First received
Last updated
Start date February 1, 2019
Est. completion date May 1, 2019

Study information
Verified date May 2020
Source Ain Shams University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The purpose of this study is to evaluate the effect of sub anesthetic dose of ketamine on vasopressor (Ephedrine) requirement to prevent maternal hypotension after spinal anesthesia in caesarean section.

Recruitment information / eligibility
Status Completed
Enrollment 80
Est. completion date May 1, 2019
Est. primary completion date April 1, 2019
Accepts healthy volunteers No
Gender Female
Age group 18 Years to 40 Years
Eligibility Inclusion Criteria:

- Physical status American Society of Anesthesiologist(ASA) I or II. Full term pregnancy

Exclusion Criteria:

- ,Pre-eclampsia.

- Chronic hypertension.

- Cardiovascular troubles.

- any contraindications to spinal anesthesia as back infection , coaguolopathy , patient refusal

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Ketamine
patients will receive sub- anesthetic dose of ketamine 0.5 mg/kg in 3 ml of isotonic saline after spinal anesthesia
• isotonic saline
patients will receive 3 ml of isotonic saline after spinal anesthesia

Locations
Country Name City State
Egypt Ain Shams University hospitals Cairo

Sponsors (1)
Lead Sponsor Collaborator
Ain Shams University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary incidence of hypotension after spinal anesthesia sub- anesthetic dose of ketamine will be given and blood pressure will be recorded every 2 minutes till delivery , every 5 minutes till end of surgery 5 hours
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