MEV to Block the Posterior and Lateral Cords of the Infraclavicular Brachial Plexus

Anesthesia Clinical Trial

— LSIB  

Official title:

Minimum Effective Volume (MEV95%) of Ropivacaine 7.5 mg/ml to Block the Posterior and Lateral Cords of the Infraclavicular Brachial Plexus

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03329456
• Other study ID #: Musso
• Status: Completed
• Phase: Phase 4
• Start date: October 30, 2017
• Est. completion date: April 1, 2018

Study information

• Verified date: October 2017
• Source: University Hospital of North Norway
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The investigators have recently shown that LSIB in combination with a suprascapular and a cervical plexus block is a very good alternative for arthroscopic shoulder surgery. However, the investigators believe the total volume of local anesthetic for LSIB may be reduced. For shoulder surgery there is no need to block the medial cord and the investigators therefore hypothesize a significantly lower MEV95% by applying a selective lateral and posterior cord block

Description:

The MEV for a successful block in 50% of the participants will be determined by using the staircase up-and-down method introduced by Dixon and Massey. Logistic regression and probit transformation will be applied to estimate the MEV for a successful block in 95% of the participants.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 23
• Est. completion date: April 1, 2018
• Est. primary completion date: April 1, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• . Inclusion criteria are American Society of Anesthesiologists (ASA) physical status I-III, age between 18 and 70 years and body mass index (BMI) between 20 and 35 kg/m2.

Exclusion Criteria:

• Exclusion criteria are pregnancy, patients with contraindications to regional anesthesia, allergy to LAs, patients taking opioids regularly due to chronic pain, use of anticoagulation drugs other than acetylsalicylic acid or dipyridamole, atrioventricular block, diabetes.

Related Conditions & MeSH terms

• Anesthesia
• Shoulder Disease

Intervention

Drug:
• Ropivacaine
Minimum effective volume

Locations

Country	Name	City	State
Norway	University Hospital of North Norway	Tromsø	Troms

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital of North Norway

Country where clinical trial is conducted

Norway, 

References & Publications (1)

Musso D, Flohr-Madsen S, Meknas K, Wilsgaard T, Ytrebø LM, Klaastad Ø. A novel combination of peripheral nerve blocks for arthroscopic shoulder surgery. Acta Anaesthesiol Scand. 2017 Oct;61(9):1192-1202. doi: 10.1111/aas.12948. Epub 2017 Aug 4. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Minimum effective volume (95%)		30 minutes