TEAS to Reduce Propofol Consumption During General Anesthesia

Anesthesia Clinical Trial

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Official title:

Effect of Transcutaneous Electrical Acupoint Stimulation on Propofol Consumption During General Anesthesia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02314650
• Other study ID #: XJH-A-2014-6-25-01
• Status: Completed
• Phase: N/A
• Start date: August 25, 2015
• Est. completion date: December 29, 2017

Study information

• Verified date: November 2022
• Source: Air Force Military Medical University, China
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The study is aimed at whether transcutaneous electrical acupoint stimulation (TEAS) during general anesthesia could reduce the need for propofol in patients undergoing minor surgery.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 162
• Est. completion date: December 29, 2017
• Est. primary completion date: December 28, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Patients undergoing minor surgeries including laparoscopic surgery and breast surgery under general anesthesia

• Patients with written informed consent

Exclusion Criteria:

• Patients with difficulty to communicate,including psychiatric disorder and Alzheimer's disease

• Patients with drug abuse

• Patients with disease of central nervous system

• Patients with renal or hepatic dysfunction

Related Conditions & MeSH terms

• Anesthesia

Intervention

Other:
• acupoint stimulation
stimulation was given at acupoints
• non-acupoint stimulation
stimulation was given at non-acupoints
• electrodes attached
electrode were attached to skin

Locations

Country	Name	City	State
China	Xijing Hospital	Xi'an	Shaanxi

Sponsors (1)

Lead Sponsor	Collaborator
Air Force Military Medical University, China

Country where clinical trial is conducted

China, 

References & Publications (2)

Fassoulaki A, Paraskeva A, Patris K, Pourgiezi T, Kostopanagiotou G. Pressure applied on the extra 1 acupuncture point reduces bispectral index values and stress in volunteers. Anesth Analg. 2003 Mar;96(3):885-890. doi: 10.1213/01.ANE.0000048713.41657.D3. — View Citation

Nayak S, Wenstone R, Jones A, Nolan J, Strong A, Carson J. Surface electrostimulation of acupuncture points for sedation of critically ill patients in the intensive care unit--a pilot study. Acupunct Med. 2008 Mar;26(1):1-7. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	propofol consumption		from induction to the end of surgery,at an average of 1 hour
Secondary	time to awake		from end of propofol infusion to open eyes to verbal command,at an average of 30 minutes
Secondary	time to extubation		from end of propofol infusion to open eyes to verbal command,at an average of 30 minutes
Secondary	effect site concentration of propofol at awake		from end of propofol infusion to open eyes to verbal command,at an average of 30 minutes
Secondary	highest sedation score during stay at postanesthesia care unit		from end of surgery to discharge from post anesthesia care unit, at an average of 1 hour
Secondary	nausea and vomiting during stay at postanesthesia care unit		30min after surgery