Anesthesia Clinical Trial
— HMPR1Official title:
Clinical Comparison of Hemodynamic Parameters Using Invasive Versus Non-invasive Continuous Blood-pressure Technology During a Total Intravenous Anaesthesia (TIVA).
During general anesthesia the basic non-invasive monitoring of hemodynamic parameters (blood
pressure, O2-saturation, cardiogram) is crucial. It can be enhanced to so called "extended
hemodynamic monitoring" depending on the operation and patient. Frequently an invasive
arterial cannula is used to provide continuous information on the blood pressure. This
invasive method is very accurate and clinically established, but can be linked to adverse
effects e.g. reduction of the circulation flow distal of the canulla, haematoma, infection
etc. ccNexfin (Edwards Lifescience) is a finger cuff measuring the blood pressure in a
non-invasive manner. It thus offers beat-to-beat information even about the extended
hemodynamic parameters as cardiac output (CO), cardiac index (CI), stroke volume (SV),
stroke volume index (SVI) and stroke volume variation (SSV), if connected to the clinical
platform EV1000 (Edwards Lifescience).
Assuming that the two methods are equal we plan to measure extended hemodynamic parameters
before, during induction and during ongoing anesthesia both invasive and non-invasive. Data
will be recorded every 30sec.
Clinical evaluation of the ccNexfin technology in respect to extended hemodynamic parameters
is to our knowledge rare and further assessment in this field is needed to offer patients a
potentially equally reliable but less invasive monitoring. Furthermore the study should
model the effect of remifentanil, propofol or its combination on haemodynamics .
Status | Completed |
Enrollment | 40 |
Est. completion date | October 2015 |
Est. primary completion date | June 2015 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - elective surgery with the necessity of an arterial catheter Exclusion Criteria: - patient not consented - peripheral vascular disease |
Observational Model: Case-Only, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Germany | University Hospital | Erlangen | Bavaria |
Lead Sponsor | Collaborator |
---|---|
University of Erlangen-Nürnberg Medical School |
Germany,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Mean arterial pressure | during anesthesia induction | No | |
Secondary | Cardiac output | during anesthesia induction | No | |
Secondary | Stroke volume variation | during anaesthesia induction | No | |
Secondary | Stroke volume | during anesthesia induction | No | |
Secondary | Heart rate | during anaesthesia induction | No |
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT04279054 -
Decreased Neuraxial Morphine After Cesarean Delivery
|
Early Phase 1 | |
Active, not recruiting |
NCT04580030 -
Tricuapid Annular Plane Sistolic Excursion Before General Anesthesia Can Predict Hypotension After Induction
|
||
Completed |
NCT03640442 -
Modified Ramped Position for Intubation of Obese Females.
|
N/A | |
Recruiting |
NCT04099693 -
A Prospective Randomized Study of General Anesthesia Versus Anesthetist Administered Sedation for ERCP
|
||
Terminated |
NCT02481999 -
Pre- and Postoperative EEG-Monitoring for Children Aged From 0,5 to 8 Years
|
||
Completed |
NCT04235894 -
An Observer Rating Scale of Facial Expression Can Predict Dreaming in Propofol Anesthesia
|
||
Recruiting |
NCT05525104 -
The Effect of DSA on Recovery of Anaesthesia in Children (Het Effect Van DSA op Het Herstel na Anesthesie Bij Kinderen).
|
N/A | |
Recruiting |
NCT05024084 -
Desflurane and Sevoflurane Minimal Flow Anesthesia on Recovery and Anesthetic Depth
|
Phase 4 | |
Completed |
NCT04204785 -
Noise in the OR at Induction: Patient and Anesthesiologists Perceptions
|
N/A | |
Completed |
NCT03277872 -
NoL, HR and MABP Responses to Tracheal Intubation Performed With MAC Blade Versus Glidescope
|
N/A | |
Terminated |
NCT03940651 -
Cardiac and Renal Biomarkers in Arthroplasty Surgery
|
Phase 4 | |
Terminated |
NCT02529696 -
Measuring Sedation in the Intensive Care Unit Using Wireless Accelerometers
|
||
Completed |
NCT05346588 -
THRIVE Feasibility Trial
|
Phase 3 | |
Terminated |
NCT03704285 -
Development of pk/pd Model of Propofol in Patients With Severe Burns
|
||
Recruiting |
NCT05259787 -
EP Intravenous Anesthesia in Hysteroscopy
|
Phase 4 | |
Completed |
NCT02894996 -
Does the Response to a Mini-fluid Challenge of 3ml/kg in 2 Minutes Predict Fluid Responsiveness for Pediatric Patient?
|
N/A | |
Completed |
NCT05386082 -
Anesthesia Core Quality Metrics Consensus Delphi Study
|
||
Terminated |
NCT03567928 -
Laryngeal Mask in Upper Gastrointestinal Procedures
|
N/A | |
Recruiting |
NCT06074471 -
Motor Sparing Supraclavicular Block
|
N/A | |
Completed |
NCT04163848 -
CARbon Impact of aNesthesic Gas
|