Anesthesia Clinical Trial
Official title:
Determination of the Minimum Effective Volume of Local Anesthetic Using Ultrasound Guidance for Interscalene Brachial Plexus Block
The purpose of this study is to determine the minimum effective volume of local anesthetic for interscalene brachial plexus block using ultrasound guidance and nerve stimulator guidance.
This will be a single group assignment, double-blind, up-down sequential allocation study.
Interscalene brachial plexus block (ISBPB) is a common nerve block given to patients who are
undergoing shoulder surgery. This block has a low, but still significant, rate of
complications. Reducing the volume of local anesthetic given during the block may allow some
of these complications to be avoided. Participants will undergo ISBPB under ultrasound and
nerve stimulator guidance. Patients will initially receive 15mL of local anesthetic
(bupivacaine 0.5% with epinephrine). The volume used for each subsequent patient depends
upon the success or failure of the previous patient's block - a failure will cause the
volume given to increase by 1.0 mL, while a success will cause the volume to decrease by the
same amount.
The goal of this study is to determine the minimum effective anesthetic volume of
bupivacaine 0.5% providing anesthesia in patients when using ultrasound and nerve stimulator
to guide placement of the block. The secondary outcome will be the evaluation of
diaphragmatic function and post-surgery analgesia.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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