Anesthesia Clinical Trial
Official title:
The Effect of Pharamocogenetices on Anesthesia Induction With Propofol
Propofol, (2,6-diisopropylphenol) is a short-acting anesthetic drug used for induction and
maintenance of anesthesia.
The aim of this study is to evaluate plasma concentrations of propofol in relation to depth
of anesthesia, measured by continuous EEG and to correlate plasma concentrations with
genetic analyses of liver enzymes responsible for drug elimination.
Our hypothesis is that there is an individual requirement of Propofol plasma concentration
depending on genetic differences in drug elimination.
200 patients, ASA classification 1, planned for elective surgery of a duration of at least
30 minutes will be included in this study.
n/a
Observational Model: Cohort, Time Perspective: Prospective
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