Glasgow Coma Scales and General Anesthesia

Anesthesia Awareness Clinical Trial

Official title:

The Effect of Glasgow Coma Scales on General Anesthesia in Neurosurgery Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03521414
• Other study ID #: TÜTF-GOKAEK 2013/127
• Status: Completed
• Phase: N/A
• Start date: July 3, 2013
• Est. completion date: November 5, 2015

Study information

• Verified date: April 2018
• Source: Trakya University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The study evaluates the general anesthesia management with BIS monitorization in terms of hemodynamic stability, drug concentrations and drug consumption in patients who underwent surgery due to intracranial pathology and who were divided in three different GCS groups.

Description:

BIS monitoring is mostly used for anesthesia depth and sedation level follow-up, however it can also be used for monitoring consciousness after resuscitation of cases with acute brain injury and cardiac arrest. It is not always possible to monitor and objectively measure the changes in the level of consciousness in clinical practice. Therefore, device-based methods have been introduced in monitoring the state of consciousness. Bispectral index (BIS) monitoring may be preferred in follow up of the state of consciousness in critical patients such as those with acute brain injury, in terms of ease of use, ability to obtain numerical results and continuous monitoring. BIS monitoring is mostly used for follow up of anesthesia depth and sedation level, while it can also be applied for monitoring state of consciousness following resuscitation in cases with acute brain injury and cardiac arrest.In this study, we aimed to investigate general anesthesia management performed by bispectral index monitoring in patients who underwent surgery due to intracranial pathology and with different Glasgow Coma Scales.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 45
• Est. completion date: November 5, 2015
• Est. primary completion date: February 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• 18 and 65 years

• ASA II-III

• intracranial surgery

Exclusion Criteria:

• Patients with additional disease (electrolyte impairment, uremia, etc.),

• liver and renal failure affecting consciousness level other than intracranial pathology

Related Conditions & MeSH terms

• Anesthesia Awareness
• Intraoperative Awareness

Intervention

Device:
• Bispectral index (BIS) monitoring
When the patients were taken to the operation table, they were monitored with the BIS. we used sevoflurane drug

Drug:
• Sevoflurane
we used sevoflurane drug at inoperative

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Trakya University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	BIS, Consumption of the inhalation agents	Preoperative, intraoperative and postoperative BIS values were recorded. The total; amount of opioid consumed was recorded from the infusion pump.	200 minutes