Clinical Trials Logo

Clinical Trial Summary

This is a pilot clinical trial to evaluate whether the medical management of early pregnancy failure with mifepristone and misoprostol is an effective and acceptable treatment. Subjects with early pregnancy failure receive mifepristone followed 24 hours later by vaginal misoprostol for medical management. Subjects then return on study day 3 for a repeat ultrasound to assess passage of pregnancy tissue. subjects who still have a gestational sac present at Day 3 receive a second dose of vaginal misoprostol. All subjects have a follow-up at Day 15, by phone for those who passed the pregnancy with the first dose of misoprostol, and in person for those who received a second dose. Questionnaires are administered at the beginning and end of the study to determine acceptability.


Clinical Trial Description

n/a


Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00177372
Study type Interventional
Source University of Pittsburgh
Contact
Status Completed
Phase Phase 4
Start date January 2005
Completion date September 2005

See also
  Status Clinical Trial Phase
Completed NCT05216952 - Ulipristal Acetate for Use in Early Pregnancy Loss Phase 2
Completed NCT05198050 - Letrozole in Induction of Abortion of Anembryonic Pregnancy N/A
Terminated NCT00468299 - MiMi: A Randomized Trial of Mifepristone and Misoprostol for Treatment of Early Pregnancy Failure N/A