Effect of Pumpkin Seed Oil on Hair Growth in Men With Androgenetic Alopecia

Androgenic Alopecia Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01852487
• Other study ID #: Pumpkin0912
• Status: Completed
• Phase: N/A
• First received: May 9, 2013
• Last updated: May 10, 2013
• Start date: February 2012
• Est. completion date: December 2012

Study information

• Verified date: May 2013
• Source: Dream Plus
• Contact: n/a
• Is FDA regulated: No
• Health authority: Korea: Ministry of Education, Science, and Technology
• Study type: Interventional

Clinical Trial Summary

Androgenic alopecia is the most common cause of hair loss in men. Finasteride and minoxidil are available in treatment of androgenetic alopecia, although the former causes decreased libido or ejaculate volume, erectile dysfunction, the latter causes scaling, itching of the scalp. Recently, Pulpkin Seed Oil shows some improved clinical efficacy on scalp hair growth in men with androgenetic alopecia, but there is no evidence to support this.

The investigators conducted a randomized, double-blind, placebo-controlled efficacy and tolerability trial of Pumpkin seed oil (400mg/day)therapy in male patients with androgenetic alopecia.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 80
• Est. completion date: December 2012
• Est. primary completion date: December 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• 18 to 65 years of age

• Androgenetic alopecia of Norwood-Hamilton scale grade II-V

Exclusion Criteria:

• Severe medical problems including renal problems, prostate diseases, diabetes mellitus o

• Patients who took any medicine which can affect the hair growth in recent 3 months.

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Alopecia
• Alopecia Areata
• Androgenic Alopecia

Intervention

Dietary Supplement:
• 400mg /day during 6 months

Locations

Country	Name	City	State
Korea, Republic of	Pusan National University Yangsan Hospital	Yangsan	Gyeongsangnam-do

Sponsors (1)

Lead Sponsor	Collaborator
Dream Plus

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	hair analysis using phototrichogram		at weeks 12 and 24	No
Primary	investigator assessment score using photographs of scalp hair		at weeks 12 and 24	No
Secondary	patient self-assessment scores		at weeks 12 and 24	No