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Clinical Trial to Evaluate Safety and Efficacy of CCX168 in ANCA-Associated Vasculitis

ANCA-associated Vasculitis Clinical Trial

Official title:
A Randomized, Double-Blind, Placebo-Controlled, Dose Assessment Phase 2 Study to Evaluate the Safety and Efficacy of CCX168 in Subjects With Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis

Clinical Trial Summary

The aim of this trial is to test the safety and efficacy of two dose regimens of the complement C5a receptor CCX168 in patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Funding Source - FDA OOPD

Clinical Trial Description

Complement 5a and its receptor C5aR (CD88) is involved in the pathogenesis of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis. This is a randomized, double-blind, placebo-controlled Phase 2 study to evaluate the safety and efficacy of the C5aR inhibitor CCX168 in subjects with ANCA-associated vasculitis. The aim of this trial is to test the safety and efficacy of two dose regimens of the complement C5a receptor CCX168 in patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02222155
Study type Interventional
Source ChemoCentryx
Contact
Status Completed
Phase Phase 2
Start date February 4, 2015
Completion date July 19, 2016
View Details
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