Analgesics Clinical Trial
Official title:
Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine
Verified date | April 2022 |
Source | The University of Texas Health Science Center, Houston |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this study is to show that the effect of 3% 2-chloroprocaine prior to epidural morphine administration will be not inferior to the effect of epidural 2% lidocaine with 1:200,000 epinephrine on total opioid use for 24h
Status | Completed |
Enrollment | 44 |
Est. completion date | July 11, 2021 |
Est. primary completion date | May 11, 2021 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 50 Years |
Eligibility | Inclusion Criteria: - pregnant patients - live singleton pregnancy Exclusion Criteria: - BMI >40 - obstructive sleep apnea - drug abuse - chronic pain - chronic opioid use - nonfunctioning epidural |
Country | Name | City | State |
---|---|---|---|
United States | The University of Texas Health Science Center at Houston | Houston | Texas |
Lead Sponsor | Collaborator |
---|---|
The University of Texas Health Science Center, Houston |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Total Amount of Opioid Used | 24 hours after epidural morphine administration | ||
Secondary | Total Amount of Opioid Used | 12 hours after epidural morphine administration | ||
Secondary | Total Amount of Opioid Used | 8 hours after epidural morphine administration | ||
Secondary | Total Amount of Opioid Used | 4 hours after epidural morphine administration | ||
Secondary | Pain as Measured by a 11 Point Verbal Scale | scale ranges form 0-10, higher number indicating more pain | 4,8, 12 and 24 hours after epidural morphine administration | |
Secondary | Number of Participants Who Had Mild, Moderate or Severe Nausea as Measured by a 3 Point Scale | scale ranges from non,mild and moderate-severe | 4,8, 12 and 24 hours after epidural morphine administration | |
Secondary | Number of Participants Who Had Mild, Moderate or Severe Pruritis as Measured by a 3 Point Scale | scale ranges from non,mild and moderate-severe | 4,8, 12 and 24 hours after epidural morphine administration | |
Secondary | Time Until First Opioid Request | Up to 48 hours after epidural morphine administration |
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