Role of Ultrasound Guided Transversus Abdominis Plane Block in Pain Control After Hepatectomy

Analgesia Clinical Trial

— U/STAP  

Official title:

Ultrasound Guided Oblique Subcostal Transversus Abdominis Plane Block(TAP) Versus Both Subcostal and Posterior TAP Block as Postoperative Analgesia in Hepatectomy

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06224179
• Other study ID #: M S 96/2021
• Status: Not yet recruiting
• Phase: N/A
• Start date: February 1, 2024
• Est. completion date: June 1, 2024

Study information

• Verified date: January 2024
• Source: Ain Shams University
• Contact: Ahmed El-Dolah, lecturer of Anesthesia
• Phone: +20111113077
• Email: a_wagih82[@]yahoo.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Inadequately managed acute pain following abdominal surgery originates from somatic pain signals in the abdominal wall and is linked to various unfavorable postoperative outcomes. These consequences encompass patient distress, respiratory complications, delirium, myocardial ischemia, extended hospital stays, an elevated risk of chronic pain, heightened analgesic consumption, delayed bowel function, and an increased need for rescue analgesics.

This study aims to assess the postoperative analgesic efficacy of ultrasound-guided Transversus Abdominis Plane (TAP) block using oblique subcostal and posterior approaches in hepatectomy.

Description:

Pain control is vital to achieve enhanced recovery after abdominal surgeries . TAP block had been demonstrated to improve pain related outcomes after abdominal surgeries.

Postoperative pain management for patients undergoing hepatic resection is a challenge due to the risk of perioperative liver dysfunction.TAP block is a promising regional analgesic technique. This study aimed to evaluate the effect of US-guided subcostal approach versus combination of both subcostal and posterior approaches of TAP block

The patients will be randomly divided into two groups :

group A will recieve oblique subcostal TAP block and group B will recieve both subcostal and posterior TAP block .

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 40
• Est. completion date: June 1, 2024
• Est. primary completion date: May 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• ASA I and II patients. aged 18 to 50 years. 70 to 80 kg.

Exclusion Criteria:

• patients under 18 years of age.

• History of Allergic reactions to study drugs.

• Opioid or analgesic abuse, and chronic treatment with opioids, or non-steroidal anti-inflammatory drugs.

• History of bleeding tendency or coagulopathy .

Related Conditions & MeSH terms

• Analgesia

Intervention

Procedure:
• ultrasound guided subcostal TAP block
patients will be randomly divided into two groups using a computer generated random number chart. Group A received ultrasound guided subcostal TAP block,
• ultrasound guided combined posterior and subcostal TAP block
patients will be randomly divided into two groups using a computer generated random number chart. Group B received ultrasound guided combined posterior and subcostal TAP block,

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Ain Shams University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	postoperative analgesia (VAS) during the 1st 24 hours in ICU	Pain will be assessed on admission and at 2, 4, 8, 12 and 24 hours at rest and with passive flexion of hip and knee joint using visual analogue scale (VAS) ranging from 0 for no pain to 10 for worst pain.	24 hours