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Opioid Sparing Analgesia: Dexmedetomidine Versus Lidocaine for Intracranial Surgeries in Children

Analgesia Clinical Trial

Official title:
Opioid Sparing Analgesia: Intraoperative Infusion Dexmedetomidine Versus Lidocaine for Intracranial Surgeries in Children

Clinical Trial Summary

Perioperative pain control is necessary in children as inadequate treatment may lead to progression of perception of pain and development of chronic pain in the future. Anesthetists tend to adopt approach to perioperative control of pain by non-opioid drugs that mediate pain modulation. Its use as opioid sparing analgesia in different surgeries leading to mixed results.

Clinical Trial Description

Site of study: This study will be carried out in neurosurgical operating rooms of Zagazig University Hospitals. b. Sample size: A pilot study was done to estimate percent of children need intraoperative fentanyl was (10%) for dexmedetomidine group, and ( 40%) for lidocaine group, at 0.05 α error and 0.2 β error . Sample size was calculated using Open Epi software, is 32 children in each group. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04535089
Study type Interventional
Source Zagazig University
Contact
Status Completed
Phase Phase 1/Phase 2
Start date October 1, 2020
Completion date October 1, 2021
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