The Analgesic Effect of Butorphanol After Cesarean Section

Analgesia Clinical Trial

Official title:

The Analgesic Effect of Butorphanol After Cesarean Section

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04490980
• Other study ID #: TJ-C20200119
• Status: Not yet recruiting
• Phase: N/A
• Start date: August 1, 2020
• Est. completion date: December 31, 2020

Study information

• Verified date: June 2020
• Source: Tongji Hospital
• Contact: Xun Gong, Doctor
• Phone: 13886174675
• Email: gongxun4019[@]163.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

We evaluated the clinical effect of Butorphanol on postoperative analgesia by observing the vital signs of patients, general condition of newborns and pain assessment.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 100
• Est. completion date: December 31, 2020
• Est. primary completion date: November 30, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

Healthy women at term (37 to 42 weeks of gestation), who desired cesarean section were eligible to participate. undergoing ;No drug sensitive history

Exclusion Criteria:

Patients with a history of anesthetics allergy and patients with preterm labor, multiple pregnancies and severe obstetric complications

Related Conditions & MeSH terms

• Analgesia

Intervention

Drug:
• butorphanol
Observed group:Intravenous drip of Butorphanol in patients after cesarean section;control group: intravenous drip of saline in patients after cesarean section

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Tongji Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	change from Visual Analogue Score for pain	VAS is the most common pain scale for quantification. The score is higher, the patient will be more painful. That will indicate if the analgesia is effective. Visual analog scale (VAS) ranging from 0 to 10 (with 10 representing the worst pain imaginable) to measure the degree of pain for participants	assess VAS at 24 hours, 25 hours, 26 hours, 27 hours, 30 hours, 36 hours after the cesarean section
Secondary	heart rates	heart rates(bpm)	at 24 hours, 30 hours, 36 hours after the cesarean section
Secondary	jaundice index of the newborn,1 minute and 5 minutes Apgar score	Neonatal Apgar scores at the first and fifth minute.The score indicates the infant s' conditions, including heart rate, breathing, muscle tone, reflex response, color. Each characteristic is given an individual score; two points for each of the five categories if all is completely well; then all scores are totaled. The score is from 0 to 10.	jaundice index: 24 hours, 48 hours, 72 hours after the cesarean section
Secondary	blood pressure	blood pressure(mmHg)	at 24 hours, 30 hours, 36 hours after the cesarean section
Secondary	breath	breath(bpm)	at 24 hours, 30 hours, 36 hours after the cesarean section
Secondary	pulse	pulse(bpm)	at 24 hours, 30 hours, 36 hours after the cesarean section