Action Observation and Motor Imagery Induced Hypoalgesia in Asymptomatic Subjects

Analgesia Clinical Trial

Official title:

Action Observation and Motor Imagery Induced Hypoalgesia in Asymptomatic Subjects

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03959449
• Other study ID #: uammadrid8
• Status: Completed
• Phase: N/A
• Start date: June 5, 2019
• Est. completion date: July 15, 2019

Study information

• Verified date: July 2019
• Source: Universidad Autonoma de Madrid
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study evaluates the influence of motor imagery and the observation of actions on pain perception. Participants in this study are asymptomatic subjects who will perform an IM and AO protocol of an aerobic exercise.

Description:

Motor Imagery (MI) is defined as a dynamic mental process that involves the representation of an action, in an internal way, without its actual motor execution. The Action Observation (AO) evokes an internal, real-time motor simulation of the movements that the observer is perceiving visually. Both mental processes trigger the activation of the neurocognitive mechanisms that underlie the planning and execution of voluntary movements in a manner that resembles how the action is performed in a real manner. The phenomenon of exercise-induced hypoalgesia is well known. This is why it has been suggested that these techniques could produce pain modulation similar to that produced by real exercise.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: July 15, 2019
• Est. primary completion date: June 30, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Age between 18 and 60

• Healthy and with no pain subjects

Exclusion Criteria:

• Any cognitive impairment that hindered viewing of audiovisual material.

• Difficulty understanding or communicating.

• Presence of systemic pathology, Central Nervous System or rheumatic disease.

• Inadequate understanding of the Spanish language to follow instructions for measuring and treatment.

• Collaboration of pregnant women.

• Underage subjects

• Subjects with pain at the time of the study.

Related Conditions & MeSH terms

• Analgesia
• Exercise

Intervention

Behavioral:
• Action Observation plus motor imagery
Action observation (video) and motor imagery of running.
• Motor imagery
Motor imagery of running
• Exercise plus action Observation and motor imagery
Real exercise of running during 6 min plus action observation (video) and motor imagery of running.

Locations

Country	Name	City	State
Spain	CSEU La Salle	Madrid

Sponsors (1)

Lead Sponsor	Collaborator
Universidad Autonoma de Madrid

Country where clinical trial is conducted

Spain, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pain pressure threshold	Pressure Pain Threshold (PPT) is one of these tests and it is defined as the minimum force applied which induces pain. The measurement shall be carried out by using an algometer (pressure device that induces mechanical stimuli) is to standardize the amount of pressure applied in the neck region. The reliability of pressure pain thresholds according to raters or measurement frequencies is relatively high	Change from baseline and immediately post-intervention
Secondary	Visual and Kinesthetic Motor Imagery Ability	Visual and Kinesthetic Motor Imagery Ability will be measured with Movement Imagery Questionnaire-Revised (MIQ-R). MIQ-R has four movements repeated in two subscales, a visual and a kinesthetic one. Additionally, a score between 1 and 7 is assigned, with 1 representing difficulty in picturing the motor image or difficulty in feeling the movement previously made, and 7 representing the maximum ease. The internal consistencies of the MIQ-R have been consistently adequate with Cronbach's a coefficients ranging above 0.84 for the total scale, 0.80 for de visual subscale and 0.84 for the kinesthetic subscale (Campos & González, 2010).	Immediately before the intervention
Secondary	The degree of physical activity	The degree of physical activity was objectified through the The International Physical Activity Questionnaire (IPAQ) questionnaire, which allows the subjects to be divided into three groups according to their level of activity, which can be high, moderate, and low or inactive. The IPAQ consists of 7 questions about the frequency, duration and intensity of activity (moderate and intense) performed in the last seven days, as well as walking and sitting time on a workday. The IPAQ scoring protocol assigns the following MET values to walking, moderate, and vigorous intensity activity: 3.3 METs, 4.0 METs, and 8.0 METs, respectively.	Immediately before the intervention
Secondary	Kinesiophobia	Fear of movement or kinesiophobia will be quantified with the Spanish version of the Kinesiophobia Tampa Scale (TSK-11). This instrument demonstrates reliability and validity in patients with chronic pain, being shorter than the original scale. The total score ranges from 11 to 44 points, with the highest scores indicating greater fear of a new injury due to movement	Immediately before the intervention
Secondary	Electrodermal Activity	Electrodermal Activity will be measured through the use of two electrodes that recorded changes in conductance through the skin located at the back of the dominant hand	Change in electrodermal activity after 5 minutes post-intervention
Secondary	Respiration Rate	Respiration Rate will be measured through a pressure transducer located in the centre of the chest, where it was fixed by a strap	Change in electrodermal activity after 5 minutes post-intervention
Secondary	Respiration Rate	Heart Rate will be measured by three electrodes located in the left area of the chest. One of the electrodes was placed in the middle zone while a second electrode was positioned on the lateral side, and a third one on the lower left side, below the first electrode.	Change in electrodermal activity after 5 minutes post-intervention