Tow Techniques of Adductor Canal Block for Analgesia After Total Knee Replacement

Analgesia Clinical Trial

Official title:

Ultrasound-guided Continuous Adductor Canal Block for Analgesia After Total Knee Replacement: Comparison of Block at the Entrance and Middle of the Canal

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03942133
• Other study ID #: CXL1
• Status: Completed
• Phase: N/A
• Start date: May 11, 2019
• Est. completion date: December 16, 2019

Study information

• Verified date: December 2019
• Source: Peking Union Medical College Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study compares the tow technique of continues adductor canal block for total knee replacement surgery. Half participants will receive catheterization at the entrance of the adductor canal, while the other half will receive catheterization at the middle point of the adductor canal.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 62
• Est. completion date: December 16, 2019
• Est. primary completion date: December 8, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• 18-80 years

• Knee-arthroscopy

• Written consent

• ASA I-III

• BMI 19-35

Exclusion Criteria:

• Unable to communicate with the investigators (e.g., a language barrier or a neuropsychiatric disorder).

• coagulopathy or on anticoagulant medication

• Allergic reactions toward drugs used in the trial

• History of substance abuse

• Infection at injection site

• Can not be mobilised to 5 meters of walk pre-surgery

Related Conditions & MeSH terms

• Analgesia
• Nerve Block
• Total Knee Arthroplasty

Intervention

Procedure:
• ultrasound-guided short-axis placement of catheter at the entrance of the adductor canal
Ultrasound probe is placed at the entrance of the adductor canal in short axis ,insertion of a PAJUNK Contiplex S catheter with the tip of the catheter located at the entrance of the canal
• ultrasound-guided long-axis placement of catheter at the middle of the adductor canal
Ultrasound probe is placed at the middle of the adductor canal in long axis with the caphelad end of the probe aligned with the entrance of the canal. insertion of a PAJUNK Contiplex S catheter with the tip of the catheter located at the middle of the canal

Locations

Country	Name	City	State
China	Peking Union Medical College Hospital	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
Peking Union Medical College Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	cumulative sulfentanil consumption at 24 hours after surgery		24 hours after surgery
Secondary	the strength of quadriceps femoris	Quadriceps strength was assessed on a 0-5 scale as per the Medical Research Council Scale quadriceps motor strength(0 = no voluntary contraction possible, 1 = muscle flicker, but no movement of limb, 2 = active movement only with gravity eliminated, 3 = movement against gravity but without resistance, 4 = movement possible against some resistance and 5 = normal motor strength against resistance)	0,2,4,8,24,48 hours postoperatively
Secondary	The pain scores at rest determined by the numeric rating scale (NRS, 0-10)	11-point numerical rating scale (NRS; 0, no pain; 10, maximum pain imaginable).	at 0,2,4,8,24,48 hours postoperatively
Secondary	The pain scores on adduction of the keen determined by the numeric rating scale (NRS, 0-10)	11-point numerical rating scale (NRS; 0, no pain; 10, maximum pain imaginable).	at 0,2,4,8,24,48 hours postoperatively
Secondary	incidence of postoperative nausea and vomiting (PONV)		within 48 hours after surgery
Secondary	Patient satisfaction with anesthesia	Patient satisfaction with anesthesia was assessed using a 5-point scale (5, very satisfied; 4, satisfied; 3, neither satisfied nor dissatisfied; 2, dissatisfied; 1, very dissatisfied)	within 5th day after surgery
Secondary	complications	Record complications including catheter dislodgment, puncture point infection, leakage,falling down,et al.	within 3days after surgery
Secondary	cumulative sulfentanil consumption at other time points after surgery		2,4,8,48 hours postoperatively