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Clinical Trial Summary

The investigators aimed to evaluate tramadol-sparing effect of intravenous (IV) ibuprofen in patients undergoing percutaneous nephrolithotomy (PCNL).


Clinical Trial Description

Eighty patients who will undergoing PCNL are randomized to intravenous paracetamol (n=40) and intravenous ibuprofen (n=40) groups. Patients will receive 100 mL of physiologic saline with 1 g IV paracetamol or 800 mg IV ibuprofen 30 minutes before the end of the operation and postoperatively 6, 12 and 18 hours after PCNL in the paracetamol and ibuprofen groups, respectively. Patients in both groups will receive intravenous tramadol with patient controlled analgesia device (PCA).

The visual analog scale (VAS) will used to evaluate pain intensity scores in the postoperative period.

Total tramadol consumption, mean VAS score in the 1, 8 and 24 hours, demographic variables, operative variables, and side effects will record. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03016650
Study type Interventional
Source Inonu University
Contact Muharrem Ucar, Asst.Prof.
Phone +90 422 341 06 60
Email umuharrem@hotmail.com
Status Not yet recruiting
Phase Phase 4
Start date January 2017
Completion date May 2017

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