Analgesia Clinical Trial
Official title:
Implementation and Evaluation of a Paediatric Nurse-driven Sedation Protocol in a Paediatric Intensive Care Unit
Management of analgesia and sedation is an integral component of the medical care of a
critically-ill child. Its role is to assure comfort and safety to a patient undergoing
painful cares and technical procedures; it can also be, in particular situations like acute
respiratory distress syndrome or acute brain injury, a full processing treatment.
Sedation involves, most of the time, the association of an opioid and a sedative. The use of
these drugs is difficult in children, because of a specific metabolism, inducing tolerance
and withdrawal in case of prolonged administration.
The COMFORT-BEHAVIOR (COMFORT-B) scale is a validated, simple, reliable and reproducible
score evaluating sedation and analgesia. Sedation scoring systems must be used regularly to
avoid inadequate sedation.
Excessive sedation is associated with poor outcomes like prolonged mechanical ventilation,
longer hospitalisation and more frequent withdrawal symptoms. Adult and paediatric data
suggest that goal-directed sedation algorithms allow a more appropriate adaptation of the
treatment to the patient's need and permit a reduction in the duration of mechanical
ventilation.
The objective was to evaluate the impact of a nurse-driven sedation protocol in a paediatric
intensive care unit on duration of mechanical ventilation, total doses and duration of
medications, Paediatric Intensive Care Unit (PICU) length of stay, incidence of
ventilator-associated-pneumonia and occurrence of withdrawal.
n/a
Time Perspective: Retrospective
Status | Clinical Trial | Phase | |
---|---|---|---|
Not yet recruiting |
NCT05534230 -
Dexmedetomidine for Pain Reduction in CABG
|
N/A | |
Recruiting |
NCT06275698 -
HONEY for the Treatment of POst-Tonsillectomy Pain
|
N/A | |
Recruiting |
NCT04436224 -
Hydromorphone for ICU-analgesia in Patients With Non-mechanical Ventilation
|
Phase 4 | |
Not yet recruiting |
NCT04548323 -
Hypoalgesic Effects of Walking and Running Imagined
|
||
Completed |
NCT06054945 -
Clinical Impact of IPACK Block Addition to Suprainguinal Fascia Iliaca Block
|
||
Completed |
NCT04394481 -
Extension of Analgesia by Combined Injection of Dexamethasone and Dexmedetomidine After Arthroscopic Shoulder Surgery
|
Phase 4 | |
Completed |
NCT04690647 -
The Efficacy of Suprainguinal Fascia Iliaca Compartment Block for Analgesia After Elective Total Hip Replacement.
|
N/A | |
Completed |
NCT05034601 -
ESPB vs TPVB for Postoperative Analgesia After the Nuss Procedure
|
N/A | |
Completed |
NCT03740815 -
Feasibility of Serratus Plane Block Associated With Sedation in Axillary Dissection
|
N/A | |
Recruiting |
NCT05454202 -
Assessment of the Interest of ANI in the Non-communicating Patient in Palliative Care
|
||
Recruiting |
NCT04554186 -
Serratus Anterior Plane Block Versus Thoracic Paravertebral Block.
|
N/A | |
Not yet recruiting |
NCT06393777 -
Effectiveness of Pre-administered Natural Sweet-tasting Solution (Honey) for Decreasing Pain of Needle Insertion
|
N/A | |
Suspended |
NCT04860635 -
Safety of F14 Following Total Knee Replacement
|
Phase 2/Phase 3 | |
Not yet recruiting |
NCT04519463 -
The Effect of Local Anesthesia With Lidocaine During Insertion and Removal of Nasal Packing
|
Early Phase 1 | |
Completed |
NCT02916342 -
Interscalene Block Versus Combined Supraprascapular: Axillary Nerve Blocks
|
Phase 4 | |
Completed |
NCT03206554 -
Local Infiltration Analgesia in Total Knee Arthroplasty
|
Phase 2 | |
Not yet recruiting |
NCT02549118 -
Tenoxicam for Intrapartum Analgesia
|
Phase 2 | |
Not yet recruiting |
NCT02190760 -
Comparison Between Perineural and Systemic Effect of Dexamethasone for Interscalene Brachial Plexus Block.
|
N/A | |
Completed |
NCT01789606 -
Self-Selection and Actual Use Trial of Ibuprofen 600 mg Immediate Release/Extended Caplet
|
Phase 3 | |
Completed |
NCT01299584 -
ULTIVA Post Marketing Surveillance
|
N/A |