Anal Cancer Clinical Trial
Official title:
Comparison of Flocked vs. Dacron Swab for Anal Cytology, Correspondence With High Resolution Anoscopy
RATIONALE: Doctors use a swab to collect cell samples when testing for anal cancer and human
papillomavirus. It is not yet known which type of swab is more effective in collecting cell
samples for anal Pap tests and human papillomavirus tests in men who have sex with men.
PURPOSE: This clinical trial is comparing two types of swabs in collecting cell samples for
anal Pap tests and human papillomavirus tests in men who have sex with men.
OBJECTIVES:
- To determine whether the anal cytology screening outcome derived from specimens
collected by a flocked nylon swab are equivalent to those derived from Dacron swab
specimens in men who have sex with men.
- To determine whether the number and type-specific identification for human
papillomavirus derived from specimens collected by a flocked nylon swab are equivalent
to those derived from Dacron swab specimens.
OUTLINE: Dry sterile Dacron swabs and flocked nylon swabs are used to collect intra-anal
cytology specimens for anal Pap testing and human papillomavirus typing. Participants undergo
a digital rectal examination and high-resolution anoscopy. If lesions are identified, an anal
biopsy is performed for histological examination.
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