Iron Metabolism in Dragon Boat Athletes

Anaemia Clinical Trial

Official title:

Iron Metabolism in Dragon Boat Athletes - An Analysis of Changes in Blood Count Parameters Under Sport-specific Stress

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01431118
• Other study ID #: Gi-02-2011
• Status: Completed
• Phase: N/A
• First received: August 31, 2011
• Last updated: July 21, 2012
• Start date: April 2011
• Est. completion date: April 2012

Study information

• Verified date: July 2012
• Source: University of Giessen
• Contact: n/a
• Is FDA regulated: No
• Health authority: Germany: Ethics Commission
• Study type: Interventional

Clinical Trial Summary

The purpose of the study is:

• To investigate the effect of sport-specific stress in the iron metabolism of dragon boat athletes

• To investigate the effects of sport-specific stress in the activity of pro-hepcidin and hepcidin

Description:

This investigation evaluates the effects of sport-specific stress in iron metabolism of dragon boat athletes. Recent studies showed a significant increase in hepcidin activity under exercise (Röcker L. et al.(2005): Iron regulatory protein hepcidin is increased in female athletes after a marathon. European Journal of Applied Physiology, S. 95, 569-571)which possibly influences the iron metabolism.

In particular in this investigation the activity of pro-hepcidin and hepcidin under sport-specific stress is analysed. Therefore elite dragonboat athletes will be included to this study. Every athlete is tested once. At one exercise day from every athlete the iron metabolism especially the change of hepcidin, prohepcidin and iron before and after a specific dragonboat intervention is analysed.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: April 2012
• Est. primary completion date: April 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• athletes performing dragon boat sport

Exclusion Criteria:

• acute clinically significant intercurrent diseases

Study Design

Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Single Blind (Investigator), Primary Purpose: Diagnostic

Related Conditions & MeSH terms

• Anaemia

Intervention

Other:
• specific dragon boating training intervention
male athletes of the german national dragon boat team performing three specific training units at one day
• specific dragon boat intervention
women athletes of the german national dragon boat team performing two specific training units and one weight lifting test at one day

Locations

Country	Name	City	State
n/a

Sponsors (3)

Lead Sponsor	Collaborator
University of Giessen	Deutscher Drachenboot Verband e.V., MVZ für Laboratoriumsmedizin Koblenz

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	change from Baseline in prohepcidin after performing dragonboating	one meassurement of prohepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day	pre and post exercise intervention at the same day	No
Secondary	haematocrit	one meassurement of haematocrit immediate before and within three hours after performing two to four specific dragonboat intervention at the same day	pre and post exercise intervention at the same day	No
Secondary	value of reticulocytes	one meassurement of reticulocytes immediate before performing two to four specific dragonboat interventions	pre exercise	No
Secondary	value of hypochromic erythrocytes	one meassurement of hypochromic erythrocytes immediate before performing two to four specific dragonboat interventions	pre exercise	No
Secondary	change from Baseline in serum iron after performing dragonboating	one meassurement of serum iron immediate before and within three hours after performing two to four specific dragonboat interventions at the same day	pre and post exercise intervention at the same day	No
Secondary	value of transferrin	one meassurement of transferrin immediate before performing two to four specific dragonboat interventions	pre exercise	No
Secondary	value of transferrin saturation	one meassurement of transferrin saturation immediate before performing two to four specific dragonboat interventions	pre exercise	No
Secondary	value of ferritin	one meassurement of ferritin immediate before performing two to four specific dragonboat interventions	pre exercise	No
Secondary	change from Baseline in hepcidin after performing dragonboating	one meassurement of hepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day	pre and post exercise intervention at the same day	No