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Sleep Disorders and the Onset and Progression of ALS

Amyotrophic Lateral Sclerosis Clinical Trial

Official title:
Effect of Sleep Disorder on Onset and Progression of Amyotrophic Lateral Sclerosis

Clinical Trial Summary

200 cases of ALS patients were collected to explore whether sleep disorders are related to earlier onset age, and whether sleep disorders accelerate the progress of ALS and shorten the survival time of ALS patients.

Clinical Trial Description

200 patients with ALS were collected. 1) sleep disorders were assessed by Pittsburgh sleep quality index (PSQI) and Epworth Sleepiness Scale (epworth) at baseline Sleeping Scale，ESS）； 2) Name, age, gender and onset site were collected to explore whether sleep disorders were associated with earlier onset age; 3) The patients' function (ALSFRS-R) at baseline and every 3 months within 2 years were collected, and the end-point time (death and invasive breathing) was recorded to evaluate whether sleep disturbance accelerated the decline of patients' function and shortened their short-term survival. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04952038
Study type Observational
Source Peking University Third Hospital
Contact Dongsheng Fan
Phone +86 13701023871
Email dsfan@sina.com
Status Recruiting
Phase
Start date August 1, 2020
Completion date March 31, 2022
View Details
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