Answer ALS: Individualized Initiative for ALS Discovery

Status Completed

Clinical Trial Summary

Creation of a large repository of induced pluripotent stem cells (iPSC), bio-fluid samples (blood and spinal fluid (optional)), and cell lines for ALS gene identification. This will be combined carefully with collected measures of the pattern of the symptoms people with ALS have and how these change over time. People with other motor neuron diseases and healthy controls will be included as comparisons

Clinical Trial Description

Patients will have 5 study visits; screening, 3, 6, 9 and 12 months. There will be a one year post-participation follow-up period, during which they will receive an email or phone call interview once every 3 months. During the first year, samples will be collected, breathing, muscle strength, spasticity, general function and cognitive behavior will be assessed. Healthy controls will have 2 study visits during which blood samples will be collected and questionnaires given. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02574390
Study type	Observational [Patient Registry]
Source	Johns Hopkins University
Contact
Status	Completed
Phase
Start date	December 2015
Completion date	January 1, 2020

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See also
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Answer ALS: Individualized Initiative for ALS Discovery — AnswerALS

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms