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Phase 3 Study of Dexpramipexole in ALS — EMPOWER  

Amyotrophic Lateral Sclerosis Clinical Trial

Official title:
A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study of the Safety and Efficacy of Dexpramipexole in Subjects With Amyotrophic Lateral Sclerosis

Clinical Trial Summary

The purpose of this study is to determine whether dexpramipexole (150 mg twice daily) is safe and effective in the treatment of Amyotrophic Lateral Sclerosis (ALS).

Clinical Trial Description

Amyotrophic Lateral Sclerosis (ALS) is a rapidly progressive, degenerative disease of motor neurons in the brain and spinal cord that leads to muscle atrophy and spasticity in limb and bulbar muscles resulting in weakness and loss of ambulation, oropharyngeal dysfunction, weight loss, and ultimately respiratory failure. The purpose of this study is to determine whether dexpramipexole (150 mg twice daily) is safe and effective in the treatment of ALS. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01281189
Study type Interventional
Source Knopp Biosciences
Contact
Status Completed
Phase Phase 3
Start date March 2011
Completion date November 2012
View Details
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