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Donor-derived CAR-T Cells in the Treatment of AML Patients

AML Clinical Trial

Official title:
A Study to Evaluate the Safety and Efficacy of Donor-derived CAR-T Cells in the Treatment of Patients With Relapsed or Refractory Acute Myeloid Leukemia

Clinical Trial Summary

This is a clinical study to evaluate the safety and efficacy of donor-derived CAR-T cells in the treatment of patients with relapsed or refractory acute myeloid leukemia in China.

Clinical Trial Description

This is a single-center, single-arm, open-label study. This study is planned to enroll about 9 subjects with relapsed or refractory acute myelogenous leukemia and 9 matched donors for leukapheresis and CAR-T cells manufacture. Donor-derived CAR-T cells were then infused intravenously into subjects, in a dose-escalating 3+3 design. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04766840
Study type Interventional
Source Beijing Immunochina Medical Science & Technology Co., Ltd.
Contact FEI Wu
Phone 15801390058
Email wufei@immunochina.com
Status Not yet recruiting
Phase Phase 1
Start date March 1, 2021
Completion date December 1, 2023
View Details
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