Creatine to Augment Bioenergetics in Alzheimer's — CABA  

Alzheimer's Disease Clinical Trial

Official title: Creatine to Augment Bioenergetics in Alzheimer's

Status Recruiting

Clinical Trial Summary

By doing this study, researchers hope to see if creatine monohydrate is a helpful treatment for people with Alzheimer's disease.

Clinical Trial Description

Alzheimer's disease is a progressive brain disorder that causes memory and thinking problems. Current medications may temporarily help with symptoms but cannot stop the disease from getting worse. As such, new treatments that slow or stop the disease from progressing are needed.

There is some evidence from animal studies that taking creatine monohydrate may improve thinking in Alzheimer's disease and be good for brain health. However, no studies have looked at creatine monohydrate supplementation in humans with Alzheimer's.

Creatine monohydrate is a dietary supplement regulated by the FDA. This is a study that will test if taking creatine monohydrate may be a helpful treatment for people with Alzheimer's disease. In this study, investigators will will evaluate:

1. Whether persons with Alzheimer's disease are able to easily take creatine monohydrate for 8 weeks.

2. Whether creatine monohydrate affects thinking function in people with Alzheimer's Disease.

3. Whether creatine monohydrate affects certain biochemicals in the brain and body.

4. Whether creatine monohydrate improves muscle size and strength. ;

Related Conditions & MeSH terms

• Alzheimer Disease
• Alzheimer's Disease

• NCT number: NCT05383833
• Study type: Interventional
• Source: University of Kansas Medical Center
• Contact: Aaron N Smith, MS, RD
• Phone: 913-229-5935
• Email: asmith71@kumc.edu
• Status: Recruiting
• Phase: N/A
• Start date: December 12, 2022
• Completion date: June 30, 2025