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Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT05113732
Other study ID # IUC-PT
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date November 1, 2021
Est. completion date May 1, 2022

Study information

Verified date October 2021
Source Istanbul University-Cerrahpasa
Contact Kübra Nur Menengiç, MSc
Phone +90 05054400987
Email kmenengic@gmail.com
Is FDA regulated No
Health authority
Study type Observational [Patient Registry]

Clinical Trial Summary

This study aimed to investigate relationship between cognitive function and functional mobility in Alzheimer's disease.


Description:

Our hypothesis is that the decrease in cognitive function in individuals with Alzheimer's disease is associated with the level of functional mobility. Sociodemographic information of participants will be recorded. Cognition will assessed with Montreal Cognitive Assessment (MoCA), global score and MoCA's visuospatial executive functions, naming, attention, language, abstract thinking, delayed recall, orientation sub-scores will recorded. Functional mobility will assessed Timed Up and Go Test and 5 Times Sit&Stand Test.


Recruitment information / eligibility

Status Not yet recruiting
Enrollment 64
Est. completion date May 1, 2022
Est. primary completion date January 1, 2022
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: - Diagnosed with Alzheimer's disease according to the National Institute of --Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease (NINCDS-ADRDA) criteria, - Over 65 years old, - Cases who could understand the instructions given in Turkish were included in the study, - Having ambulation skill independently or with walking aid. Exclusion Criteria: - Dementia with Lewy bodies, frontotemporal dementia and one of the other types of dementia, - Having a pulmonary, neurological, musculoskeletal or rheumatological disease that may prevent exercise, - Unstable medical condition (uncontrolled diabetes or hypertension, deep vein thrombosis, etc.), - Subjects with visual or auditory deficits or behavioral problems that would make communication difficult were not included in the study.

Study Design


Locations

Country Name City State
Turkey Istanbul University-Cerrahpasa Istanbul

Sponsors (1)

Lead Sponsor Collaborator
Istanbul University-Cerrahpasa

Country where clinical trial is conducted

Turkey, 

Outcome

Type Measure Description Time frame Safety issue
Primary Montreal Cognitive Assesment (MoCA) MoCA assesses cognitive skills such as visuospatial / executive functioning, object naming, memory, attention, language, abstraction, orientation. Higher scores reflect the better performance. Baseline
Primary Timed Up and Go Test Timed Up and Go Test measures the level of functional mobility skills and, assess fall risk and balance. The time elapsed between standing up from the sitting position, walking the distance of 3 meters, coming back and sitting back on the chair is recorded. The shorter time reflect the better performance. Baseline
Primary 5 Time Sit to Stand Test 5 Time Sit to Stand Test measures the level of functional mobility skills and, assess fall risk and lower extremity strength. The test measures the time taken to stand five times from a sitting position as quickly as possible. The shorter time reflect the better performance. Baseline
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