Efficacy of ORM-12741 on Agitation/Aggression Symptoms in Alzheimer's

Status Completed

Clinical Trial Summary

This study evaluates the effect of ORM-12741 on agitation/aggression symptoms in Alzheimer's disease. Two thirds of the patients will receive ORM-12741 and one third will receive placebo.

Clinical Trial Description

ORM-12741 is a potent and selective alpha-2C adrenoceptor (AR)-antagonist. Previous results suggest that the compound may have positive effects on both cognitive and neuropsychiatric symptoms of Alzheimer's Disease. In this study, the effect of ORM-12741 will be evaluated on agitation/aggression symptoms and other neuropsychiatric symptoms. Furthermore, cognition and psychotic and depressive symptoms will be evaluated. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02471196
Study type	Interventional
Source	Orion Corporation, Orion Pharma
Contact
Status	Completed
Phase	Phase 2
Start date	August 14, 2015
Completion date	December 4, 2017

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Efficacy of ORM-12741 on Agitation/Aggression Symptoms in Alzheimer's Disease — Nebula

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms