Alzheimer's Disease Clinical Trial
Official title:
Evaluating the Effects of the Novel GLP-1 Analogue, Liraglutide, in Patients With Mild Alzheimer's Disease (ELAD Study)
This is a 12-month, multicentre randomised double-blind placebo-controlled Phase IIb study in patients with mild Alzheimer's dementia (AD). Patients will be randomised on a 1:1 ratio to receive liraglutide or matching placebo.
The investigators aim to recruit patients with mild Alzheimer's dementia as defined by the
National Institute of Neurological and Communicative Disorders and Stroke - Alzheimer's
Disease and Related Disorder Association (NINCDS-ADRDA) Criteria for Probable Alzheimer's
Dementia or meeting Dubois criteria for early AD, with Mini Mental State Evaluation score of
at least 20 out of a maximum of 30 and a CDR Global score of 0.5 or 1.
.
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