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Clinical Trial Summary

The recent clinical authorization of amyloid Positon Emission Tomography (PET) in France represents a crucial step for the nuclear medicine community involved in the diagnosis of Alzheimer's disease (AD).


Clinical Trial Description

The recent clinical authorization of amyloid Positon Emission Tomography (PET) in France represents a crucial step for the nuclear medicine community involved in the diagnosis of Alzheimer's disease (AD). At the era of Amyloid, Tau, Neurodegeneration (ATN) biomarkers, amyloid PET fills a need in patients with an atypical or mixed clinical presentation, in particular young patients (< 65 years old), when the lumbar puncture is contraindicated or not feasible for technical reasons. Importantly, a negative amyloid PET scan discards the diagnosis of AD. Furthermore, early phase imaging of amyloid PET allows to estimate the perfusion neuronal state, increasing the diagnostic value of such PET radiotracer. Its role could be further developed in routine care for the selection and monitoring of promising disease modifiers therapies. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06467981
Study type Observational
Source Central Hospital, Nancy, France
Contact Antoine VERGER, MD, PhD
Phone 03 83 15 55 67
Email a.verger@chru-nancy.fr
Status Not yet recruiting
Phase
Start date July 1, 2024
Completion date December 30, 2024

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