Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation

Status Recruiting

Clinical Trial Summary

The investigators will evaluate the theory that Alzheimer's disease-related memory impairment derives from the inefficient orchestration of rhythmic activity at the level of large-scale cortical networks. The results as expected to elucidate AD-related pathophysiology and set groundwork for the development of drug-free interventions for improving memory in AD and related dementias.

Clinical Trial Description

The investigators hypothesize that AD-related memory impairments emerge from large-scale functional dysconnectivity, and by stimulating the brain noninvasively with extremely weak levels of electrical current, the investigators may be able to re-synchronize connectivity and stabilize or improve memory and cognitive function, measured behaviorally. The experimental intervention involves the application of low-intensity, high-definition, transcranial electrical current stimulation while subjects perform a variety of computer-based tasks that probe memory and cognitive function. ;

Study Design

Related Conditions & MeSH terms

Alzheimer Disease

Clinical Trial Details

NCT number	NCT06094192
Study type	Interventional
Source	Boston University Charles River Campus
Contact	Robert M. G. Reinhart, PhD
Phone	(617) 353-9481
Email	rmgr@bu.edu
Status	Recruiting
Phase	N/A
Start date	December 20, 2023
Completion date	May 31, 2028

View Details

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