Financial Incentives and Recruitment to the APT Webstudy

Alzheimer Disease Clinical Trial

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Official title:

A Randomized Trial of Financial Incentives for the Recruitment of County Health System Patients to the Alzheimer Prevention Trials (APT) Webstudy

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06033066
• Other study ID #: UP-22-01037
• Status: Recruiting
• Phase: N/A
• Start date: September 27, 2023
• Est. completion date: March 2026

Study information

• Verified date: December 2023
• Source: University of Southern California
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This single-blind, three-arm, randomized, controlled trial will assess the impact of messages and financial incentives on the enrollment of demographically diverse individuals to the Alzheimer Prevention Trials (APT) Webstudy. The APT Webstudy is a novel, online registry that employs quarterly cognitive testing using validated platforms. The APT Webstudy implements fully remote assessments, coordinated by the Alzheimer's Therapeutic Research Institute (ATRI) under USC IRB #HS-17-00746. The purpose of the current study is to test whether we can increase enrollment of diverse individuals into the registry. To do this, we will work with Contra Costa Regional Medical Center (CCRMC), the county public hospital and its affiliated health centers in Contra Costa County, California, to test whether sending messages with and without financial incentives to patients who receive primary care with the health system can increase enrollment to the APT Webstudy. The investigators hypothesize that 1) a certain small financial incentive and an award opportunity based incentive (or a drawing with a prize) will increase enrollment rates of CCHS members into the APT Webstudy relative to the control group. The investigators further hypothesize that the award opportunity incentive will increase the enrollment rate of CCRMC patients into the APT Webstudy more than a certain financial incentive with the same expected value.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 48000
• Est. completion date: March 2026
• Est. primary completion date: March 2026
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 50 Years and older

Eligibility

Inclusion Criteria:

To be eligible to participate in this study, an individual must meet all of the following criteria:

• Patients empaneled at Contra Costa Regional Medical Center (CCRMC), the county public hospital and its affiliated health centers.

• Age 50 or older

• Literate in either English or Spanish

Exclusion Criteria:

• Below age 50

• Documentation of prior dementia diagnosis

Related Conditions & MeSH terms

• Alzheimer Disease
• Dementia
• Preclinical Alzheimer's Disease
• Prodromal Alzheimer's Disease

Intervention

Behavioral:
• Financial Incentives
Small financial incentive or prize incentive
• Message
Message inviting participant to enroll

Locations

Country	Name	City	State
United States	Contra Costa Health Plan	Martinez	California

Sponsors (4)

Lead Sponsor	Collaborator
University of Southern California	Alzheimer's Therapeutic Research Institute, American Heart Association, Schaeffer Center for Health Policy & Economics

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Enrollment status into the APT Webstudy	APT Webstudy enrollment rate based on completion of at least one of the two APT Webstudy cognitive assessments (Cognitive Function Instrument [CFI] and/or Cogstate Brief Battery).	2-weeks
Secondary	Cost per enrollee	Cost to acquire an enrollment	annual
Secondary	Completion of cognitive assessments within the APT Webstudy	Completion of both APT Webstudy cognitive assessments (Cognitive Function Instrument [CFI] and/or Cogstate Brief Battery).	2-weeks

External Links

•   APT Webstudy