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Effect of CAFfeine on Cognition in Alzheimer's Disease — CAFCA  

Alzheimer Disease Clinical Trial

Official title:
Multicentre, Randomized, Double-blind, Placebo-controlled Trial Evaluating the Effect of a 30-week Caffeine Treatment on Cognition in Alzheimer's Disease at Beginning to Moderate Stages

Clinical Trial Summary

Sporadic Alzheimer's disease is a multifactorial illness arising a major medico-economic stakes for our aging societies. There is currently no curative treatment available. Coffee is a complex beverage with psychostimulant properties whose main effective element, caffeine, has a pleiotropic effect on the central nervous system. Caffeine pharmacological properties enable its use like an Alzheimer's disease symptomatic treatment. Its supposed benefits mustn't obscure anxiety and insomnia caffeine effect at large dose, which Alzheimer's patients might be more vulnerable. The main study objective is to evaluate placebo-controlled caffeine efficacy (30 treatments weeks) on cognitive decline in Alzheimer's disease dementia at beginning to moderate stage (MMSE 16-24).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04570085
Study type Interventional
Source University Hospital, Lille
Contact Thibaud LEBOUVIER, MD,PhD
Phone 03 20 44 60 21
Email thibaud.lebouvier@chru-lille.fr
Status Recruiting
Phase Phase 3
Start date March 1, 2021
Completion date November 2024
View Details
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