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Clinical Trial Summary

A Pilot open labeled study of Tacrolimus in Alzheimer's Disease.


Clinical Trial Description

This study will investigate the neurobiological effect of tacrolimus in persons with MCI and dementia due to AD by measuring biomarkers of target engagement in immune response, amyloid-b, tau and neurodegeneration in CSF, functional connectivity with MRI and EEG, and cognition. Study objectives include: ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04263519
Study type Interventional
Source Massachusetts General Hospital
Contact
Status Withdrawn
Phase Phase 2
Start date December 1, 2021
Completion date January 1, 2023

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