The PACO Study ("Personnalité Alzheimer COmportement") — PACO  

Alzheimer Disease Clinical Trial

Official title: The Role of Personality in the Occurrence of Behavioural Disorders in Patients Suffering From Alzheimer Disease

Status Recruiting

Clinical Trial Summary

Alzheimer's disease is characterised by a loss of cognitive functions and behavioural problems as set out under the term "Behavioural and psychological symptoms of dementia (BPSD)". The impact of BPSD in everyday life has heavy consequences for the patient and their family. The precocity of incidence, the frequency and the intensity of the BPSD are associated with a rapid decline in cognitive functions, an alteration in the activities of daily living, and a decrease in the quality of life for both the patient and the helper, an increased risk of hospitalisation and of institutionalisation as well as an increase in the cost to the health system. A greater understanding of the risk factors for the occurence of the BPSD would better allow the detection of patients who are particularly at risk for BPSD, to anticipate the crisis situations by proposing early and adapted care, and to better target the medicinal therapies. Certain observational arguments or results of retrospective studies speak in favour of the role of the basic personality in the occurence of BPSD in Alzheimer's disease. The investigators propose to clarify this role through a prospective study.

Clinical Trial Description

n/a

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label

Related Conditions & MeSH terms

• Alzheimer Disease

• NCT number: NCT01297140
• Study type: Interventional
• Source: Hospices Civils de Lyon
• Contact: Pierre KROLAK-SALMON, Professor
• Phone: 04.72.43.31.13
• Email: pierre.krolak-salmon@chu-lyon.fr
• Status: Recruiting
• Phase: N/A
• Start date: January 2009
• Completion date: November 2015