Alveolar Ridge Preservation Clinical Trial
Official title:
The Impact of Immediate Implant Placement on Alveolar Ridge Preservation Techniques: a Clinical, Volumetric and Radiological Randomized Controlled Clinical Trial.
It is well known that following the loss of a single tooth, severe hard- and soft-tissue
alterations may take place within the affected site, resulting in a subsequent reduction of
both vertical and horizontal ridge dimensions, often not allowing neither appropiate pontic
fabrication nor correct placement of endosseous implants.
Over the past 20 years, various surgical procedures, grouped under the term of "alveolar
ridge preservation" (ARP), have been introduced, aiming to maintain the existing soft and
hard tissue envelope as well as a stable ridge volume, simplifying subsequent treatment
procedures and optimizing functional and esthetic outcomes. They have been widely tested in
controlled and not controlled clinical studies with various materials and approaches, and a
number of recently published systematic reviews on this topic have confirmed the efficacy of
ARP in preventing post-extraction dimensional changes of alveolar ridges.
After these procedures a minimum of four to six months must be awaited before implant
insertion can be performed, bringing the patient compromised comfort, function and aesthetics
and needing of a second surgical procedure for the implant placement.
Dental implant insertion at the time of tooth extraction (type I or immediate placement)
reduced the number of dental appointments, of surgeries required and the overall treatment
time. Nevertheless this surgical protocol does not provide predictable outcomes, since it may
contribute towards a more pronounced bone resorption during healing. Different anatomical
factors, as the thickness of the buccal bone wall and the dimension of the horizontal gap,
may influence the dimensional changes of the alveolar crest following immediate implant
placement. Such morphological changes could lead to negative esthetic complications, such as
marginal soft tissues recessions, especially when affecting the buccal side of maxillary
sites in patients with a high smile line.
It is unknown if immediate implant placement plus grafting materials and/or barrier membranes
could influence post-extraction dimensional changes of alveolar ridges. No consensus exists
on the need for bone augmentation simultaneously with immediate implant placement.
Furthermore, no human study has yet compared dimensional changes of both hard and soft
tissues after two different treatments: an alveolar ridge preservation technique for a
subsequent implant placement, and an alveolar ridge preservation technique with an immediate
implant placement.
Hypothesis/Aims
Primary hypotesis
Placing an immediate implant into a fresh extraction site plus a bone substitute filling and
a matrix covering could negatively modify the healing patterns and thus the tissue morphology
of the ridge site with regard to:
- clinical hard tissues dimensions (bone width and height, bone volume)
- clinical soft tissues dimensions (soft tissues volume, keratinized tissues width and
thickness, muco-gingival junction position's modifications, gingival color and texture,)
Secondary hypothesis.
Placing an immediate implant into fresh extraction site plus a bone substitute filling and a
matrix covering could negatively influence tissue morphology of the preserved site with
regard to:
- clinical hard tissues dimensions (bone width and height, bone volume)
- clinical soft tissues dimensions (soft tissues volume, keratinized tissues width and
thickness, muco-gingival junction position's modifications, gingival color and texture,)
Aims:
The first aim of this study is to evaluate the possible impact on hard and soft tissue
morphological changes of placing an immediate implant in post-extraction site treated by a
bone substitute filling and a matrix covering.
The second aim of this study is to compare hard and soft tissue morphological changes in a
spontaneous healed extraction site versus a fresh extraction site treated by immediate
implant placement plus a bone substitute filling and a matrix covering
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05517798 -
Enamel Matrix Derivative for Alveolar Ridge Preservation After Tooth Extraction
|
N/A | |
Not yet recruiting |
NCT05553548 -
Alveolar Ridge Changes With Biologically Oriented Alveolar Ridge Preservation (BARP) After Tooth Extraction
|
N/A | |
Active, not recruiting |
NCT03374813 -
Efficacy of MimetikOss in Alveolar Ridge Preservation Previous to Implant Placement
|
N/A | |
Recruiting |
NCT06308536 -
Application of Concentrated Growth Factors in Alveolar Ridge Preservation
|
N/A | |
Active, not recruiting |
NCT05683509 -
Alveolar Ridge Preservation With Layered Collagen and Xenograft
|
N/A | |
Completed |
NCT02707536 -
Influence of Platelet-Rich Fibrin on Post-extraction Alveolar Ridge Healing/Preservation as a Stand-alone or Adjunct to Particulate Graft
|
N/A | |
Completed |
NCT03468998 -
The Influence of Bone Allograft Particle Sizes on the Quantity and Quality of New Bone Formation in Grafted Extraction Sockets and Edentulous Ridges
|
N/A | |
Completed |
NCT03487718 -
A 14 Weeks Longitudinal Study to Investigate the Effect of Leukocyte- Platelet Rich Fibrin Plug on the Quality of the Newly Formed Bone in Ridge Preservation Procedure Following a Tooth Extraction. It is a Clinical, Radiographic and Histomorphometric Study.
|
N/A | |
Not yet recruiting |
NCT06141239 -
2D/3D Imaging to Analyze the Regeneration Rate of Autologous Bone
|
N/A | |
Not yet recruiting |
NCT06435754 -
Hard and Soft Tissue Changes Following Vestibular Socket Preservation Versus Ice Cream Cone Technique for Management of Defective Fresh Extraction Sockets in the Esthetic Zone: A Randomized Clinical Trial
|
N/A | |
Completed |
NCT04321109 -
Alveolar Ridge Preservation Using Collagen Material and Allograft
|
N/A | |
Terminated |
NCT04719624 -
Novel Porous Bioceramic Material as a Bone Substitute
|
N/A | |
Completed |
NCT03043885 -
Ridge Preservation With Platelet Rich Fibrin Augmented With Freeze Dried Bone Allograft
|
N/A | |
Recruiting |
NCT06275789 -
Mix of Demineralized Freeze-Dried Bone Allograft and Deproteinized Bovine Bone Mineral: a Possible Solution for Alveolar Ridge Preservation?
|
N/A | |
Recruiting |
NCT04296682 -
Impact Of Soft Tissue Manipulation On Dimensional Changes After Posterior Region Extraction.
|
N/A | |
Recruiting |
NCT05601531 -
Autologous Tooth Root in Ridge Preservation
|
N/A | |
Completed |
NCT05419778 -
Alveolar Ridge Preservation Procedures
|
||
Completed |
NCT03447795 -
Alveolar Ridge Preservation Using Autogenous Tooth Graft Versus Autogenous Demineralized Dentin Graft.
|
N/A | |
Completed |
NCT05107141 -
Ridge Preservation in Molar Sites Comparing Xenograft Versus Mineralized Freeze-dried Bone Allograft
|
N/A | |
Active, not recruiting |
NCT04824235 -
Alveolar Ridge Preservation Using Amniotic Chorion Membrane
|
N/A |