Autogenous Grafts for Anterior Maxillary Horizontal Ridge Augmentation

Alveolar Ridge Augmentation Clinical Trial

Official title:

Autogenous Inlay Versus Onlay Grafts for Anterior Maxillary Horizontal Ridge Augmentation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06206577
• Other study ID #: A08040820
• Status: Completed
• Phase: N/A
• Start date: September 1, 2020
• Est. completion date: May 26, 2023

Study information

• Verified date: January 2024
• Source: Mansoura University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of the study was to compare efficacy of autogenous onlay and inlay grafts for anterior maxillary horizontal ridge augmentation.

Description:

Autogenous block graft has been used as onlay thin cortical shell and cortico-cancellous particles. The thin cortical shell acts as an autogenous biological membrane that will resist resorption and stabilize the small pieces of particulate bone. The bone block is screwed-in at a distance from the recipient site by means of titanium bone screws, and then the free space under the shell is filled with the particulate bone.

The resultant augmentation somehow resembles an iliac graft, with thick internal cancellous bone and a thin external cortical layer. This leads to an ideal graft, with a high regenerative capacity comparable to iliac bone and a stable regenerated volume with optimum osseointegration potential close to that of mandibular block grafts.

Interpositional grafts have been successfully established in restoring vertical bone height . However much less evidence is present on its use for horizontal augmentation. It is the purpose of this study to assess the efficacy of autogenous onlay corticocancellous block grafts for anterior maxillary horizontal ridge augmentation as compared to onlay block grafts.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 14
• Est. completion date: May 26, 2023
• Est. primary completion date: September 15, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 50 Years

Eligibility

Inclusion Criteria:

1. Patients with missing upper anterior tooth / teeth with horizontal ridge dimension range from 2 to 5 mm (measured 2mm below alveolar crest).

2. Adequate vertical height.

3. Having good oral hygiene.

4. being healthy, with no systemic diseases that might contraindicate receiving a dental implant

5. Patients were able to comply with the follow-up and maintenance program

Exclusion Criteria:

1. Presence of local infection or lesions at site of interest.

2. Dental history of bruxism, or other parafunctional habits.

3. Uncooperative patients.

4. Current chemotherapy or radiotherapy.

5. Patients with aggressive periodontal disease

Related Conditions & MeSH terms

• Alveolar Ridge Augmentation

Intervention

Procedure:
• Horizontal ridge augmentation by symphyseal bone block placed and fixed buccally as onlay graft
autogenous bone block harvested from chin area using piezosurgery and fixed buccally in deficient area with fixation screws
• Horizontal ridge augmentation by symphyseal bone block interpositioned in space created between buccal and lingual cortex as inlay graft
autogenous bone block harvested from chin area using piezosurgery and fixed in bone split created at deficient area with fixation screws

Locations

Country	Name	City	State
Egypt	Mansoura U	Mansoura

Sponsors (1)

Lead Sponsor	Collaborator
Mansoura University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	horizontal ridge augmentation	CBCT to assess bone gain in mm	12 months