Alveolar Bone Resorption Clinical Trial
— MRSOfficial title:
Modified Ridge Splitting Technique Using Autogenous Bone Blocks (MRS)
In this clinical study ridge splitting procedures are preformed using autogenous bone blocks. After a 3-month healing, at the time of dental implant placement bone core biopsy samples are harvested. The samples undergo micro-Ct and histomorphometric analysis.
Status | Recruiting |
Enrollment | 40 |
Est. completion date | January 1, 2023 |
Est. primary completion date | August 1, 2020 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Mandibular ridge width at least 3 mm; - Ridge height at least 11 mm; - Spongiosa between the two cortical plates at least 1 mm Exclusion Criteria: - History of uncontrolled medical disorders; - History of systemic diseases or medication that alter bone metabolism; - Poor oral hygiene; - Smoking |
Country | Name | City | State |
---|---|---|---|
Hungary | Semmelweis University | Budapest |
Lead Sponsor | Collaborator |
---|---|
Semmelweis University | Hungarian Dental Association, NSK Europe GmbH |
Hungary,
Pénzes D, Simon F, Mijiritsky E, Németh O, Kivovics M. A Modified Ridge Splitting Technique Using Autogenous Bone Blocks-A Case Series. Materials (Basel). 2020 Sep 11;13(18). pii: E4036. doi: 10.3390/ma13184036. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Clinical measurements | Clinical measurements were carried out using Williams probe (Karl Hammacher GmbH, Solingen, Germany) prior to ridge splitting surgery after the full thickness flap elevation, to evaluate the width of the alveolar ridge (preoperative measurement) and after a 3-month healing period, before implant placement (postoperative measurement). The width of the alveolar ridges was measured at 3, 10, and 15 mm from the reference point, which was the distal marginal bone of the last tooth of the quadrant. To ensure that preoperative and postoperative measurement sites corresponded, we placed the tip of the Williams probe on the reference point described and the markings of the probe to the highest ridge of the lingual cortical. | After the 3-month healing period, at the implant placement. | |
Primary | BV/TV bone volume fraction | Bone volume compared to total volume in micro-CT reconstruction | After the 3-month healing period | |
Secondary | Newly formed bone percentage | Newly formed bone area compared to total area in histomorphometry | After the 3-month healing period |
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